Cargando…

High-throughput sequencing reveals Jatrorrhizine inhibits colorectal cancer growth by ferroptosis-related genes

BACKGROUND: Colorectal cancer is a malignant tumor that poses a serious threat to human health. The main objective of this study is to investigate the mechanism by which Jatrorrhizine (JAT), a root extract from Stephania Epigaea Lo, exerts its anticancer effects in colorectal cancer. METHODS: We ini...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Lingyu, Sha, Yu, Liang, Wenken, Mo, Chune, Li, Chunhong, Deng, Yecheng, Gong, Weiwei, Hou, Xianliang, Ou, Minglin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500743/ https://www.ncbi.nlm.nih.gov/pubmed/37710311 http://dx.doi.org/10.1186/s12920-023-01619-3

Ejemplares similares

High-Throughput Sequencing Reveals That Rotundine Inhibits Colorectal Cancer by Regulating Prognosis-Related Genes
por: Huang, Lingyu, et al.
Publicado: (2023)

FAM65A as a novel prognostic biomarker in human tumors reveal by a pan-cancer analysis
por: Liang, Wenken, et al.
Publicado: (2021)

Microarray and bioinformatic analysis reveal the parental genes of m6A modified circRNAs as novel prognostic signatures in colorectal cancer
por: Liang, Wenken, et al.
Publicado: (2022)

CCR5 as a prognostic biomarker correlated with immune infiltrates in head and neck squamous cell carcinoma by bioinformatic study
por: Li, Chunhong, et al.
Publicado: (2022)

Comprehensive analysis of TCR repertoire of COVID-19 patients in different infected stage
por: Wang, Guangyu, et al.
Publicado: (2022)

Jatrorrhizine: A Review of Sources, Pharmacology, Pharmacokinetics and Toxicity
por: Zhong, Furong, et al.
Publicado: (2022)

Jatrorrhizine suppresses the antimicrobial resistance of methicillin-resistant Staphylococcus aureus
por: Yu, Haiming, et al.
Publicado: (2019)

Jatrorrhizine alleviates ulcerative colitis via regulating gut microbiota and NOS2 expression
por: Zhang, Jia Ling, et al.
Publicado: (2022)

Single-cell sequencing reveals the potential oncogenic expression atlas of human iPSC-derived cardiomyocytes
por: Ou, Minglin, et al.
Publicado: (2021)

T-cell receptor repertoires as potential diagnostic markers for patients with COVID-19
por: Hou, Xianliang, et al.
Publicado: (2021)

Jatrorrhizine inhibits colorectal carcinoma proliferation and metastasis through Wnt/β-catenin signaling pathway and epithelial–mesenchymal transition
por: Wang, Pan, et al.
Publicado: (2019)

Jatrorrhizine Suppresses Murine-Norovirus-Triggered N-GSDMD-Dependent Pyroptosis in RAW264.7 Macrophages
por: Fu, Ming, et al.
Publicado: (2023)

Jatrorrhizine Improves Endothelial Function in Diabetes and Obesity through Suppression of Endoplasmic Reticulum Stress
por: Zhou, Yan, et al.
Publicado: (2022)

Jatrorrhizine Hydrochloride Suppresses RANKL-Induced Osteoclastogenesis and Protects against Wear Particle-Induced Osteolysis
por: Li, Hui, et al.
Publicado: (2018)

A case of anti-myelin oligodendrocyte glycoprotein (MOG)-immunoglobulin G (IgG) associated disorder (MOGAD) with clinical manifestations of acute disseminated encephalomyelitis: Secondary to mycoplasma pneumoniae infection
por: Huang, Xiangui, et al.
Publicado: (2023)

Jatrorrhizine Balances the Gut Microbiota and Reverses Learning and Memory Deficits in APP/PS1 transgenic mice
por: Wang, Sheng, et al.
Publicado: (2019)

Jatrorrhizine Hydrochloride Suppresses Proliferation, Migration, and Secretion of Synoviocytes In Vitro and Ameliorates Rat Models of Rheumatoid Arthritis In Vivo
por: Qiu, Haiwen, et al.
Publicado: (2018)

Whole-genome re-sequencing for the identification of high contribution susceptibility gene variants in patients with type 2 diabetes
por: SUN, XIAOJUAN, et al.
Publicado: (2016)

Integrated analysis of B-cell and T-cell receptors by high-throughput sequencing reveals conserved repertoires in IgA nephropathy
por: Ou, Minglin, et al.
Publicado: (2018)

High-throughput transcriptome sequencing reveals the key stages of cardiovascular development in zebrafish embryos
por: Zhou, Chune, et al.
Publicado: (2022)

miR-16-5p Regulates Ferroptosis by Targeting SLC7A11 in Adriamycin-Induced Ferroptosis in Cardiomyocytes
por: Chen, Yongquan, et al.
Publicado: (2023)

Congenital Superior Sternal Cleft Isolated in a Newborn: Report of a Rare Case and a Literature Review
por: Sha, Yu, et al.
Publicado: (2022)

Integrating Spatial Transcriptomics and Single-Cell RNA-seq Reveals the Gene Expression Profling of the Human Embryonic Liver
por: Hou, Xianliang, et al.
Publicado: (2021)

Review of ferroptosis in colorectal cancer: Friends or foes?
por: Wu, Zheng, et al.
Publicado: (2023)

Whole-genome resequencing of 100 healthy individuals using DNA pooling
por: Wang, Xiaobin, et al.
Publicado: (2016)

High Throughput Sequencing of T Cell Antigen Receptors Reveals a Conserved TCR Repertoire
por: Hou, Xianliang, et al.
Publicado: (2016)

Ferroptosis-associated molecular classification characterized by distinct tumor microenvironment profiles in colorectal cancer
por: Luo, Wenqin, et al.
Publicado: (2022)

Comparative Pharmacokinetics of Berberine, Palmatine and Jatrorrhizine in Rat Plasma after Oral Administration of Rhizoma coptidis and Zuojinwan Using Liquid Chromatography-Tandem Mass Spectrometry
por: Yan, Rui, et al.
Publicado: (2012)

Jatrorrhizine reduces myocardial infarction-induced apoptosis and fibrosis through inhibiting p53 and TGF-β1/Smad2/3 pathways in mice
por: Hao, Mingxiu, et al.
Publicado: (2022)

Apoptosis Activation in Thyroid Cancer Cells by Jatrorrhizine-Platinum(II) Complex via Downregulation of PI3K/AKT/Mammalian Target of Rapamycin (mTOR) Pathway
por: Lu, KeBin, et al.
Publicado: (2020)

Jatrorrhizine Alleviates DSS-Induced Ulcerative Colitis by Regulating the Intestinal Barrier Function and Inhibiting TLR4/MyD88/NF-κB Signaling Pathway
por: Niu, Shengqi, et al.
Publicado: (2022)

Targeting Ferroptosis in Colorectal Cancer
por: Liang, Xiaojie, et al.
Publicado: (2022)

Role of ferroptosis in colorectal cancer
por: Song, Ya-Qi, et al.
Publicado: (2023)

Ferroptosis: An emerging therapeutic opportunity for cancer
por: Wang, Liyuan, et al.
Publicado: (2020)

Determination of the complexity and diversity of the TCR β-chain CDR3 repertoire in bladder cancer using high-throughput sequencing
por: Ma, Jingsheng, et al.
Publicado: (2019)

Induction mechanism of ferroptosis: A novel therapeutic target in lung disease
por: Pan, Lingyu, et al.
Publicado: (2022)

Multiomics landscape of the autosomal dominant osteopetrosis type II disease-specific induced pluripotent stem cells
por: Li, Chunhong, et al.
Publicado: (2021)

Hypereosinophilia with Concurrent Venous Thromboembolism: Clinical Features, Potential Risk Factors, and Short-term Outcomes in a Chinese Cohort
por: Liu, Yecheng, et al.
Publicado: (2020)

High‐throughput mechano‐cytometry as a method to detect apoptosis, necroptosis, and ferroptosis
por: Van der Meeren, Louis, et al.
Publicado: (2023)

Insights on Ferroptosis and Colorectal Cancer: Progress and Updates
por: Hu, Bangli, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_25ki0gae9ids7gfncdrb3bvlot