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Crosstalk between DNA methylation and hypoxia in acute myeloid leukaemia

BACKGROUND: Acute myeloid leukaemia (AML) is a deadly disease characterised by the uncontrolled proliferation of immature myeloid cells within the bone marrow. Altered regulation of DNA methylation is an important epigenetic driver of AML, where the hypoxic bone marrow microenvironment can help faci...

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Detalles Bibliográficos
Autores principales: Humphries, Sam, Bond, Danielle R., Germon, Zacary P., Keely, Simon, Enjeti, Anoop K., Dun, Matthew D., Lee, Heather J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500762/
https://www.ncbi.nlm.nih.gov/pubmed/37705055
http://dx.doi.org/10.1186/s13148-023-01566-x

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