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Proteomic alterations in the brain and blood–brain barrier during brain Aβ accumulation in an APP knock-in mouse model of Alzheimer’s disease

BACKGROUND: Blood–brain barrier (BBB) dysfunction is supposed to be an early event in the development of Alzheimer’s disease (AD). This study aimed to investigate the relationship between BBB alterations and AD progression in terms of amyloid-β peptide (Aβ) accumulation in the brains of humanized am...

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Detalles Bibliográficos
Autores principales:	Ito, Shingo, Yagi, Ryotaro, Ogata, Seiryo, Masuda, Takeshi, Saito, Takashi, Saido, Takaomi, Ohtsuki, Sumio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500766/ https://www.ncbi.nlm.nih.gov/pubmed/37705104 http://dx.doi.org/10.1186/s12987-023-00466-9

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