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Mental health problems associated with idiopathic anaphylaxis
BACKGROUND: Idiopathic Anaphylaxis (IA) is the most common anaphylactic syndrome in adults. Mental health problems associated with IA are not well recognised. We aimed to assess if patients diagnosed with IA were more likely to experience mental health problems compared to a normative Australian pop...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500772/ https://www.ncbi.nlm.nih.gov/pubmed/37705020 http://dx.doi.org/10.1186/s13223-023-00824-0 |
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author | Gardner, Logan S Tan, Zihao Brown, David Gillis, David Scott, James G. Prentice, Roger |
author_facet | Gardner, Logan S Tan, Zihao Brown, David Gillis, David Scott, James G. Prentice, Roger |
author_sort | Gardner, Logan S |
collection | PubMed |
description | BACKGROUND: Idiopathic Anaphylaxis (IA) is the most common anaphylactic syndrome in adults. Mental health problems associated with IA are not well recognised. We aimed to assess if patients diagnosed with IA were more likely to experience mental health problems compared to a normative Australian population. We additionally hypothesised that the number of anaphylactic episodes would correlate with symptoms of anxiety. METHODS: A total of 34 patients with at least one episode of IA were recruited from an adult immunology clinic. Patients were recruited as part of a separate study evaluating alternative aetiologies in IA. Mental health problems were measured using the Depression, Anxiety and Stress Scale (DASS-21). An extension of the survey included questions specifically focused on the psychological impact of IA. RESULTS: Compared to population norms, those with IA had significantly higher levels of mental health problems. Statistically significant DASS-21 scores were identified for depression 4.24 vs. 2.57 (p < 0.001), anxiety 4.76 vs. 1.74 (p < 0.012), stress 7.35 vs. 3.95 (p < 0.001) and total score 16.35 vs. 8.00 (p < 0.001). There was no association between two or more episodes of anaphylaxis and increased anxiety levels (β = 0.52, CI -2.59–3.62, p = 0.74). CONCLUSIONS: This is the first paper to demonstrate that patients living with idiopathic anaphylaxis are more symptomatic for mental illness than those in the community. Screening for mental illness and referral for psychological support should be undertaken in people with IA. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13223-023-00824-0. |
format | Online Article Text |
id | pubmed-10500772 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-105007722023-09-15 Mental health problems associated with idiopathic anaphylaxis Gardner, Logan S Tan, Zihao Brown, David Gillis, David Scott, James G. Prentice, Roger Allergy Asthma Clin Immunol Research BACKGROUND: Idiopathic Anaphylaxis (IA) is the most common anaphylactic syndrome in adults. Mental health problems associated with IA are not well recognised. We aimed to assess if patients diagnosed with IA were more likely to experience mental health problems compared to a normative Australian population. We additionally hypothesised that the number of anaphylactic episodes would correlate with symptoms of anxiety. METHODS: A total of 34 patients with at least one episode of IA were recruited from an adult immunology clinic. Patients were recruited as part of a separate study evaluating alternative aetiologies in IA. Mental health problems were measured using the Depression, Anxiety and Stress Scale (DASS-21). An extension of the survey included questions specifically focused on the psychological impact of IA. RESULTS: Compared to population norms, those with IA had significantly higher levels of mental health problems. Statistically significant DASS-21 scores were identified for depression 4.24 vs. 2.57 (p < 0.001), anxiety 4.76 vs. 1.74 (p < 0.012), stress 7.35 vs. 3.95 (p < 0.001) and total score 16.35 vs. 8.00 (p < 0.001). There was no association between two or more episodes of anaphylaxis and increased anxiety levels (β = 0.52, CI -2.59–3.62, p = 0.74). CONCLUSIONS: This is the first paper to demonstrate that patients living with idiopathic anaphylaxis are more symptomatic for mental illness than those in the community. Screening for mental illness and referral for psychological support should be undertaken in people with IA. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13223-023-00824-0. BioMed Central 2023-09-13 /pmc/articles/PMC10500772/ /pubmed/37705020 http://dx.doi.org/10.1186/s13223-023-00824-0 Text en © Crown 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Gardner, Logan S Tan, Zihao Brown, David Gillis, David Scott, James G. Prentice, Roger Mental health problems associated with idiopathic anaphylaxis |
title | Mental health problems associated with idiopathic anaphylaxis |
title_full | Mental health problems associated with idiopathic anaphylaxis |
title_fullStr | Mental health problems associated with idiopathic anaphylaxis |
title_full_unstemmed | Mental health problems associated with idiopathic anaphylaxis |
title_short | Mental health problems associated with idiopathic anaphylaxis |
title_sort | mental health problems associated with idiopathic anaphylaxis |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500772/ https://www.ncbi.nlm.nih.gov/pubmed/37705020 http://dx.doi.org/10.1186/s13223-023-00824-0 |
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