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Ehrlichia Notch signaling induction promotes XIAP stability and inhibits apoptosis

Ehrlichia chaffeensis has evolved multiple strategies to evade innate defenses of the mononuclear phagocyte. Recently, we reported the E. chaffeensis tandem repeat protein (TRP)120 effector functions as a Notch ligand mimetic and a ubiquitin ligase that degrades the nuclear tumor suppressor, F-box a...

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Detalles Bibliográficos
Autores principales:	Patterson, LaNisha L., Byerly, Caitlan D., Solomon, Regina, Pittner, Nicholas, Bui, Duc Cuong, Patel, Jignesh, McBride, Jere W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2023
Materias:	Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10501217/ https://www.ncbi.nlm.nih.gov/pubmed/37594275 http://dx.doi.org/10.1128/iai.00002-23

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