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COVID-19 in congenital heart disease patients: what did we learn?!

AIM: COVID-19 pandemic has spread widely at unpreceded pace. Cardiovascular comorbidities are significantly correlated with severe and critical illness. Nevertheless, studies examining the impact of congenital heart disease on COVID-19 severity are scarce and restricted to hospitalized patients. Thi...

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Autores principales: Zareef, Rana, Salameh, Elio, Hammoud, Rawan, Tannouri, Theresia, Bitar, Fadi, Arabi, Mariam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10501459/
https://www.ncbi.nlm.nih.gov/pubmed/37719985
http://dx.doi.org/10.3389/fcvm.2023.1235165
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author Zareef, Rana
Salameh, Elio
Hammoud, Rawan
Tannouri, Theresia
Bitar, Fadi
Arabi, Mariam
author_facet Zareef, Rana
Salameh, Elio
Hammoud, Rawan
Tannouri, Theresia
Bitar, Fadi
Arabi, Mariam
author_sort Zareef, Rana
collection PubMed
description AIM: COVID-19 pandemic has spread widely at unpreceded pace. Cardiovascular comorbidities are significantly correlated with severe and critical illness. Nevertheless, studies examining the impact of congenital heart disease on COVID-19 severity are scarce and restricted to hospitalized patients. This study aims to explore the course of COVID-19 illness, severity and complications in patients with concomitant congenital heart disease. METHODOLOGY: This study is a cross sectional survey that includes patients with congenital heart disease who are registered at the Children Heart Center at the American University of Beirut Medical Center. The survey was conducted in the pediatric cardiology outpatient clinics or remotely via phone calls. RESULTS: A total of 238 patients participated in the study, of which 47.9% had suspected or confirmed diagnosis of SARS-CoV-2 infection. The majority of patients had mild illness. The symptoms ranged between rhinorrhea (15.6%), cough (15.6%), low-grade fever (11.2%), anosmia (2.7%), ageusia (2.5%), headache (9.8%), high-grade fever (8.5%), gastrointestinal symptoms (7.6%), lethargy (6.3%), muscle aches (5.6%), difficulty breathing (5.4%), joint pain (4.7%), and chills (4.7%). 20% of the surveyed patients required treatment at home. Hospitalization and oxygen therapy was required in 3.5% of cases, while only 1.5% demanded intensive care admission. Only one fatality was encountered. CONCLUSION: COVID-19 infection in pateints with congenital heart disease exhibits a mild to moderate course, and doesn't necessarily increase risk of complicated disease. No correlation could be found between specific congenital heart lesion and disease severity.
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spelling pubmed-105014592023-09-15 COVID-19 in congenital heart disease patients: what did we learn?! Zareef, Rana Salameh, Elio Hammoud, Rawan Tannouri, Theresia Bitar, Fadi Arabi, Mariam Front Cardiovasc Med Cardiovascular Medicine AIM: COVID-19 pandemic has spread widely at unpreceded pace. Cardiovascular comorbidities are significantly correlated with severe and critical illness. Nevertheless, studies examining the impact of congenital heart disease on COVID-19 severity are scarce and restricted to hospitalized patients. This study aims to explore the course of COVID-19 illness, severity and complications in patients with concomitant congenital heart disease. METHODOLOGY: This study is a cross sectional survey that includes patients with congenital heart disease who are registered at the Children Heart Center at the American University of Beirut Medical Center. The survey was conducted in the pediatric cardiology outpatient clinics or remotely via phone calls. RESULTS: A total of 238 patients participated in the study, of which 47.9% had suspected or confirmed diagnosis of SARS-CoV-2 infection. The majority of patients had mild illness. The symptoms ranged between rhinorrhea (15.6%), cough (15.6%), low-grade fever (11.2%), anosmia (2.7%), ageusia (2.5%), headache (9.8%), high-grade fever (8.5%), gastrointestinal symptoms (7.6%), lethargy (6.3%), muscle aches (5.6%), difficulty breathing (5.4%), joint pain (4.7%), and chills (4.7%). 20% of the surveyed patients required treatment at home. Hospitalization and oxygen therapy was required in 3.5% of cases, while only 1.5% demanded intensive care admission. Only one fatality was encountered. CONCLUSION: COVID-19 infection in pateints with congenital heart disease exhibits a mild to moderate course, and doesn't necessarily increase risk of complicated disease. No correlation could be found between specific congenital heart lesion and disease severity. Frontiers Media S.A. 2023-08-31 /pmc/articles/PMC10501459/ /pubmed/37719985 http://dx.doi.org/10.3389/fcvm.2023.1235165 Text en © 2023 Zareef, Salameh, Hammoud, Tannouri, Bitar and Arabi. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cardiovascular Medicine
Zareef, Rana
Salameh, Elio
Hammoud, Rawan
Tannouri, Theresia
Bitar, Fadi
Arabi, Mariam
COVID-19 in congenital heart disease patients: what did we learn?!
title COVID-19 in congenital heart disease patients: what did we learn?!
title_full COVID-19 in congenital heart disease patients: what did we learn?!
title_fullStr COVID-19 in congenital heart disease patients: what did we learn?!
title_full_unstemmed COVID-19 in congenital heart disease patients: what did we learn?!
title_short COVID-19 in congenital heart disease patients: what did we learn?!
title_sort covid-19 in congenital heart disease patients: what did we learn?!
topic Cardiovascular Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10501459/
https://www.ncbi.nlm.nih.gov/pubmed/37719985
http://dx.doi.org/10.3389/fcvm.2023.1235165
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