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Nicotine-mediated effects in neuronal and mouse models of synucleinopathy

INTRODUCTION: Alpha-synuclein (α-Syn) aggregation, transmission, and contribution to neurotoxicity represent central mechanisms underlying Parkinson’s disease. The plant alkaloid “nicotine” was reported to attenuate α-Syn aggregation in different models, but its precise mode of action remains unclea...

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Detalles Bibliográficos
Autores principales: Fares, Mohamed Bilal, Alijevic, Omar, Johne, Stephanie, Overk, Cassia, Hashimoto, Makoto, Kondylis, Athanasios, Adame, Anthony, Dulize, Remi, Peric, Dariusz, Nury, Catherine, Battey, James, Guedj, Emmanuel, Sierro, Nicolas, Mc Hugh, Damian, Rockenstein, Edward, Kim, Changyoun, Rissman, Robert A., Hoeng, Julia, Peitsch, Manuel C., Masliah, Eliezer, Mathis, Carole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10501483/
https://www.ncbi.nlm.nih.gov/pubmed/37719154
http://dx.doi.org/10.3389/fnins.2023.1239009

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