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Nicotine-mediated effects in neuronal and mouse models of synucleinopathy
INTRODUCTION: Alpha-synuclein (α-Syn) aggregation, transmission, and contribution to neurotoxicity represent central mechanisms underlying Parkinson’s disease. The plant alkaloid “nicotine” was reported to attenuate α-Syn aggregation in different models, but its precise mode of action remains unclea...
Autores principales: | Fares, Mohamed Bilal, Alijevic, Omar, Johne, Stephanie, Overk, Cassia, Hashimoto, Makoto, Kondylis, Athanasios, Adame, Anthony, Dulize, Remi, Peric, Dariusz, Nury, Catherine, Battey, James, Guedj, Emmanuel, Sierro, Nicolas, Mc Hugh, Damian, Rockenstein, Edward, Kim, Changyoun, Rissman, Robert A., Hoeng, Julia, Peitsch, Manuel C., Masliah, Eliezer, Mathis, Carole |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10501483/ https://www.ncbi.nlm.nih.gov/pubmed/37719154 http://dx.doi.org/10.3389/fnins.2023.1239009 |
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