A novel TOX3-WDR5-ABCG2 signaling axis regulates the progression of colorectal cancer by accelerating stem-like traits and chemoresistance

The eradication of cancer stem cells (CSCs) with drug resistance confers the probability of local tumor control after chemotherapy or targeted therapy. As the main drug resistance marker, ABCG2 is also critical for colorectal cancer (CRC) evolution, in particular cancer stem–like traits expansion. H...

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Detalles Bibliográficos
Autores principales: Hao, Jiaojiao, Huang, Jinsheng, Hua, Chunyu, Zuo, Yan, Yu, Wendan, Wu, Xiaojun, Li, Liren, Xue, Guoqing, Wan, Xinyu, Ru, Liyuan, Guo, Ziyue, Han, Shilong, Deng, Wuguo, Lin, Fei, Guo, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10501593/
https://www.ncbi.nlm.nih.gov/pubmed/37708089
http://dx.doi.org/10.1371/journal.pbio.3002256

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