A safety mechanism enables tissue-specific resistance to protein aggregation during aging in C. elegans

During aging, proteostasis capacity declines and distinct proteins become unstable and can accumulate as protein aggregates inside and outside of cells. Both in disease and during aging, proteins selectively aggregate in certain tissues and not others. Yet, tissue-specific regulation of cytoplasmic...

Descripción completa

Detalles Bibliográficos
Autores principales: Jung, Raimund, Lechler, Marie C., Fernandez-Villegas, Ana, Chung, Chyi Wei, Jones, Harry C., Choi, Yoon Hee, Thompson, Maximilian A., Rödelsperger, Christian, Röseler, Waltraud, Kaminski Schierle, Gabriele S., Sommer, Ralf J., David, Della C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Short Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10501630/
https://www.ncbi.nlm.nih.gov/pubmed/37708127
http://dx.doi.org/10.1371/journal.pbio.3002284

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10501630/
https://www.ncbi.nlm.nih.gov/pubmed/37708127
http://dx.doi.org/10.1371/journal.pbio.3002284

Ejemplares similares