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The impact of the SARS-CoV-2 pandemic on the demographic, clinical and social profiles of patients admitted to the Pneumology Department for a COPD exacerbation

INTRODUCTION: Although a reduction in admissions for pathologies other than SARS-CoV-2 has been reported during the pandemic, there are hardly any specific studies in relation to COPD. The objective of this study was to analyse differences in the profile of those admitted for AEPOC and their prognos...

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Autores principales: Fernández Villar, Alberto, Golpe Gómez, Rafael, González Montaos, Almudena, Fernández García, Sara, Pazos Area, Luis, Priegue Carrera, Ana, Ruano Raviña, Alberto, Represas Represas, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10501653/
https://www.ncbi.nlm.nih.gov/pubmed/37708160
http://dx.doi.org/10.1371/journal.pone.0290156
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author Fernández Villar, Alberto
Golpe Gómez, Rafael
González Montaos, Almudena
Fernández García, Sara
Pazos Area, Luis
Priegue Carrera, Ana
Ruano Raviña, Alberto
Represas Represas, Cristina
author_facet Fernández Villar, Alberto
Golpe Gómez, Rafael
González Montaos, Almudena
Fernández García, Sara
Pazos Area, Luis
Priegue Carrera, Ana
Ruano Raviña, Alberto
Represas Represas, Cristina
author_sort Fernández Villar, Alberto
collection PubMed
description INTRODUCTION: Although a reduction in admissions for pathologies other than SARS-CoV-2 has been reported during the pandemic, there are hardly any specific studies in relation to COPD. The objective of this study was to analyse differences in the profile of those admitted for AEPOC and their prognosis during this period. METHODS: Prospective study (SocioEPOC validation cohort) conducted in two hospitals. Demographic, clinical and social characteristics were compared among patients admitted for an AECOPD before and after the declaration of the COVID-19 healthcare emergency. Mortality and the need for hospital care in the following 3 months were analysed. RESULTS: 340 patients (76.6% male, 72 years, FEV1 43.5%) were included, 174 in the post-pandemic phase. During pandemic, especially before population-level vaccination, admissions for AECOPD were in patients with more severe disease and with a higher level of eosinophils. No differences were found in social profile, except they had more informal caregivers. The mortality rate at 90 days was the same (9%), although those admitted during the pandemic came for more hospital visits in the following 3 months (53.8% vs. 42%; p = 0.003), with the pandemic phase being an independent predictor of this possibility (OR = 1.6.; 95% IC = 1.1–2.6). CONCLUSIONS: In the first few months of the pandemic, the clinical profile of patients hospitalised for an AECOPD differed from that both prior to this period and during the latter months of the pandemic, with minimal changes at the social level. Although the mortality rate were similar, unscheduled hospital visits increased during the COVID-19 pandemic.
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spelling pubmed-105016532023-09-15 The impact of the SARS-CoV-2 pandemic on the demographic, clinical and social profiles of patients admitted to the Pneumology Department for a COPD exacerbation Fernández Villar, Alberto Golpe Gómez, Rafael González Montaos, Almudena Fernández García, Sara Pazos Area, Luis Priegue Carrera, Ana Ruano Raviña, Alberto Represas Represas, Cristina PLoS One Research Article INTRODUCTION: Although a reduction in admissions for pathologies other than SARS-CoV-2 has been reported during the pandemic, there are hardly any specific studies in relation to COPD. The objective of this study was to analyse differences in the profile of those admitted for AEPOC and their prognosis during this period. METHODS: Prospective study (SocioEPOC validation cohort) conducted in two hospitals. Demographic, clinical and social characteristics were compared among patients admitted for an AECOPD before and after the declaration of the COVID-19 healthcare emergency. Mortality and the need for hospital care in the following 3 months were analysed. RESULTS: 340 patients (76.6% male, 72 years, FEV1 43.5%) were included, 174 in the post-pandemic phase. During pandemic, especially before population-level vaccination, admissions for AECOPD were in patients with more severe disease and with a higher level of eosinophils. No differences were found in social profile, except they had more informal caregivers. The mortality rate at 90 days was the same (9%), although those admitted during the pandemic came for more hospital visits in the following 3 months (53.8% vs. 42%; p = 0.003), with the pandemic phase being an independent predictor of this possibility (OR = 1.6.; 95% IC = 1.1–2.6). CONCLUSIONS: In the first few months of the pandemic, the clinical profile of patients hospitalised for an AECOPD differed from that both prior to this period and during the latter months of the pandemic, with minimal changes at the social level. Although the mortality rate were similar, unscheduled hospital visits increased during the COVID-19 pandemic. Public Library of Science 2023-09-14 /pmc/articles/PMC10501653/ /pubmed/37708160 http://dx.doi.org/10.1371/journal.pone.0290156 Text en © 2023 Fernández Villar et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Fernández Villar, Alberto
Golpe Gómez, Rafael
González Montaos, Almudena
Fernández García, Sara
Pazos Area, Luis
Priegue Carrera, Ana
Ruano Raviña, Alberto
Represas Represas, Cristina
The impact of the SARS-CoV-2 pandemic on the demographic, clinical and social profiles of patients admitted to the Pneumology Department for a COPD exacerbation
title The impact of the SARS-CoV-2 pandemic on the demographic, clinical and social profiles of patients admitted to the Pneumology Department for a COPD exacerbation
title_full The impact of the SARS-CoV-2 pandemic on the demographic, clinical and social profiles of patients admitted to the Pneumology Department for a COPD exacerbation
title_fullStr The impact of the SARS-CoV-2 pandemic on the demographic, clinical and social profiles of patients admitted to the Pneumology Department for a COPD exacerbation
title_full_unstemmed The impact of the SARS-CoV-2 pandemic on the demographic, clinical and social profiles of patients admitted to the Pneumology Department for a COPD exacerbation
title_short The impact of the SARS-CoV-2 pandemic on the demographic, clinical and social profiles of patients admitted to the Pneumology Department for a COPD exacerbation
title_sort impact of the sars-cov-2 pandemic on the demographic, clinical and social profiles of patients admitted to the pneumology department for a copd exacerbation
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10501653/
https://www.ncbi.nlm.nih.gov/pubmed/37708160
http://dx.doi.org/10.1371/journal.pone.0290156
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