Biosensor-integrated transposon mutagenesis reveals rv0158 as a coordinator of redox homeostasis in Mycobacterium tuberculosis

Mycobacterium tuberculosis (Mtb) is evolutionarily equipped to resist exogenous reactive oxygen species (ROS) but shows vulnerability to an increase in endogenous ROS (eROS). Since eROS is an unavoidable consequence of aerobic metabolism, understanding how Mtb manages eROS levels is essential yet ne...

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Detalles Bibliográficos
Autores principales: Shee, Somnath, Veetil, Reshma T, Mohanraj, Karthikeyan, Das, Mayashree, Malhotra, Nitish, Bandopadhyay, Devleena, Beig, Hussain, Birua, Shalini, Niphadkar, Shreyas, Nagarajan, Sathya Narayanan, Sinha, Vikrant Kumar, Thakur, Chandrani, Rajmani, Raju S, Chandra, Nagasuma, Laxman, Sunil, Singh, Mahavir, Samal, Areejit, Seshasayee, Aswin N, Singh, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Microbiology and Infectious Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10501769/
https://www.ncbi.nlm.nih.gov/pubmed/37642294
http://dx.doi.org/10.7554/eLife.80218

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