Retrospective immunophenotypical evaluation of MET, PD-1/PD-L1, and mTOR pathways in primary tumors and pulmonary metastases of renal cell carcinoma: the RIVELATOR study addresses the issue of biomarkers heterogeneity

AIM: In renal cell carcinoma (RCC), tumor heterogeneity generated challenges to biomarker development and therapeutic management, often becoming responsible for primary and acquired drug resistance. This study aimed to assess the inter-tumoral, intra-tumoral, and intra-lesional heterogeneity of know...

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Detalles Bibliográficos
Autores principales: Bersanelli, Melissa, Gnetti, Letizia, Pilato, Francesco Paolo, Varotti, Elena, Quaini, Federico, Campanini, Nicoletta, Rapacchi, Elena, Camisa, Roberta, Carbognani, Paolo, Silini, Enrico Maria, Rusca, Michele, Leonardi, Francesco, Maestroni, Umberto, Rizzo, Mimma, Brunelli, Matteo, Buti, Sebastiano, Ampollini, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Open Exploration Publishing 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10501858/
https://www.ncbi.nlm.nih.gov/pubmed/37720351
http://dx.doi.org/10.37349/etat.2023.00165

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