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Gestational dexamethasone exposure impacts hippocampal excitatory synaptic transmission and learning and memory function with transgenerational effects

The formation of learning and memory is regulated by synaptic plasticity in hippocampal neurons. Here we explored how gestational exposure to dexamethasone, a synthetic glucocorticoid commonly used in clinical practice, has lasting effects on offspring's learning and memory. Adult offspring rat...

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Detalles Bibliográficos
Autores principales: Luo, Mingcui, Yi, Yiwen, Huang, Songqiang, Dai, Shiyun, Xie, Lulu, Liu, Kexin, Zhang, Shuai, Jiang, Tao, Wang, Tingting, Yao, Baozhen, Wang, Hui, Xu, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10501875/
https://www.ncbi.nlm.nih.gov/pubmed/37719378
http://dx.doi.org/10.1016/j.apsb.2023.05.013