Platelet factors are induced by longevity factor klotho and enhance cognition in young and aging mice

Platelet factors regulate wound healing and can signal from the blood to the brain(1,2). However, whether platelet factors modulate cognition, a highly valued and central manifestation of brain function, is unknown. Here we show that systemic platelet factor 4 (PF4) permeates the brain and enhances...

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Detalles Bibliográficos
Autores principales: Park, Cana, Hahn, Oliver, Gupta, Shweta, Moreno, Arturo J., Marino, Francesca, Kedir, Blen, Wang, Dan, Villeda, Saul A., Wyss-Coray, Tony, Dubal, Dena B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10501899/
https://www.ncbi.nlm.nih.gov/pubmed/37587231
http://dx.doi.org/10.1038/s43587-023-00468-0

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