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A two-step workflow based on plasma p-tau217 to screen for amyloid β positivity with further confirmatory testing only in uncertain cases
Cost-effective strategies for identifying amyloid-β (Aβ) positivity in patients with cognitive impairment are urgently needed with recent approvals of anti-Aβ immunotherapies for Alzheimer’s disease (AD). Blood biomarkers can accurately detect AD pathology, but it is unclear whether their incorporat...
Autores principales: | Brum, Wagner S., Cullen, Nicholas C., Janelidze, Shorena, Ashton, Nicholas J., Zimmer, Eduardo R., Therriault, Joseph, Benedet, Andrea L., Rahmouni, Nesrine, Tissot, Cécile, Stevenson, Jenna, Servaes, Stijn, Triana-Baltzer, Gallen, Kolb, Hartmuth C., Palmqvist, Sebastian, Stomrud, Erik, Rosa-Neto, Pedro, Blennow, Kaj, Hansson, Oskar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10501903/ https://www.ncbi.nlm.nih.gov/pubmed/37653254 http://dx.doi.org/10.1038/s43587-023-00471-5 |
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