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Multi-cancer analysis reveals universal association of oncogenic LBH expression with DNA hypomethylation and WNT-Integrin signaling pathways

Limb-Bud and Heart (LBH) is a developmental transcription co-factor deregulated in cancer, with reported oncogenic and tumor suppressive effects. However, LBH expression in most cancer types remains unknown, impeding understanding of its mechanistic function Here, we performed systematic bioinformat...

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Detalles Bibliográficos
Autores principales: Young, In-Chi, Brabletz, Thomas, Lindley, Linsey E., Abreu, Maria, Nagathihalli, Nagaraj, Zaika, Alexander, Briegel, Karoline J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10501907/
https://www.ncbi.nlm.nih.gov/pubmed/37268816
http://dx.doi.org/10.1038/s41417-023-00633-y