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Neuroprotective protein ADNP-dependent histone remodeling complex promotes T helper 2 immune cell differentiation

Type 2 immune responses are critical in tissue homeostasis, anti-helminth immunity, and allergy. T helper 2 (Th2) cells produce interleukin-4 (IL-4), IL-5, and IL-13 from the type 2 gene cluster under regulation by transcription factors (TFs) including GATA3. To better understand transcriptional reg...

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Detalles Bibliográficos
Autores principales: Ferreira, Ana C.F., Szeto, Aydan C.H., Clark, Paula A., Crisp, Alastair, Kozik, Patrycja, Jolin, Helen E., McKenzie, Andrew N.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10501989/
https://www.ncbi.nlm.nih.gov/pubmed/37285842
http://dx.doi.org/10.1016/j.immuni.2023.05.010