Cargando…

Molecular basis of TASL recruitment by the peptide/histidine transporter 1, PHT1

PHT1 is a histidine /oligopeptide transporter with an essential role in Toll-like receptor innate immune responses. It can act as a receptor by recruiting the adaptor protein TASL which leads to type I interferon production via IRF5. Persistent stimulation of this signalling pathway is known to be i...

Descripción completa

Detalles Bibliográficos
Autores principales: Custódio, Tânia F., Killer, Maxime, Yu, Dingquan, Puente, Virginia, Teufel, Daniel P., Pautsch, Alexander, Schnapp, Gisela, Grundl, Marc, Kosinski, Jan, Löw, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502012/
https://www.ncbi.nlm.nih.gov/pubmed/37709742
http://dx.doi.org/10.1038/s41467-023-41420-5