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N-terminal α-amino SUMOylation of cofilin-1 is critical for its regulation of actin depolymerization

Small ubiquitin-like modifier (SUMO) typically conjugates to target proteins through isopeptide linkage to the ε-amino group of lysine residues. This posttranslational modification (PTM) plays pivotal roles in modulating protein function. Cofilins are key regulators of actin cytoskeleton dynamics an...

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Detalles Bibliográficos
Autores principales: Weng, Weiji, Gu, Xiaokun, Yang, Yang, Zhang, Qiao, Deng, Qi, Zhou, Jie, Cheng, Jinke, Zhu, Michael X., Feng, Junfeng, Huang, Ou, Li, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502023/
https://www.ncbi.nlm.nih.gov/pubmed/37709794
http://dx.doi.org/10.1038/s41467-023-41520-2