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N-terminal α-amino SUMOylation of cofilin-1 is critical for its regulation of actin depolymerization
Small ubiquitin-like modifier (SUMO) typically conjugates to target proteins through isopeptide linkage to the ε-amino group of lysine residues. This posttranslational modification (PTM) plays pivotal roles in modulating protein function. Cofilins are key regulators of actin cytoskeleton dynamics an...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502023/ https://www.ncbi.nlm.nih.gov/pubmed/37709794 http://dx.doi.org/10.1038/s41467-023-41520-2 |