Cargando…

Profiling tear film enzymes reveals major metabolic pathways involved in the homeostasis of the ocular surface

The ocular surface (OS) enzymes are of great interest due to their potential for novel ocular drug development. We aimed first to profile and classify the enzymes of the OS to describe major biological processes and pathways that are involved in the maintenance of homeostasis. Second, we aimed to co...

Descripción completa

Detalles Bibliográficos
Autores principales:	Akkurt Arslan, Murat, Brignole-Baudouin, Françoise, Chardonnet, Solenne, Pionneau, Cédric, Blond, Frédéric, Baudouin, Christophe, Kessal, Karima
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502076/ https://www.ncbi.nlm.nih.gov/pubmed/37709789 http://dx.doi.org/10.1038/s41598-023-42104-2

Ejemplares similares

Proteomic Analysis of Tears and Conjunctival Cells Collected with Schirmer Strips Using timsTOF Pro: Preanalytical Considerations
por: Akkurt Arslan, Murat, et al.
Publicado: (2021)

The Dual Effect of Rho-Kinase Inhibition on Trabecular Meshwork Cells Cytoskeleton and Extracellular Matrix in an In Vitro Model of Glaucoma
por: Buffault, Juliette, et al.
Publicado: (2022)

Comparison of Two Experimental Mouse Dry Eye Models through Inflammatory Gene Set Enrichment Analysis Based on a Multiplexed Transcriptomic Approach
por: Kessal, Karima, et al.
Publicado: (2021)

Conjunctival Inflammatory Gene Expression Profiling in Dry Eye Disease: Correlations With HLA-DRA and HLA-DRB1
por: Kessal, Karima, et al.
Publicado: (2018)

Lipid Annotation by Combination of UHPLC-HRMS (MS), Molecular Networking, and Retention Time Prediction: Application to a Lipidomic Study of In Vitro Models of Dry Eye Disease
por: Magny, Romain, et al.
Publicado: (2020)

Comparison of the ocular tolerability of a latanoprost cationic emulsion versus conventional formulations of prostaglandins: an in vivo toxicity assay
por: Liang, Hong, et al.
Publicado: (2009)

Ocular safety of cationic emulsion of cyclosporine in an in vitro corneal wound-healing model and an acute in vivo rabbit model
por: Liang, Hong, et al.
Publicado: (2012)

Cationic Emulsion-Based Artificial Tears as a Mimic of Functional Healthy Tear Film for Restoration of Ocular Surface Homeostasis in Dry Eye Disease
por: Daull, Philippe, et al.
Publicado: (2020)

Th1- and Th2-related chemokine and chemokine receptor expression on the ocular surface in endotoxin-induced uveitis
por: Trinh, Liem, et al.
Publicado: (2008)

In Vitro Inhibition of NFAT5-Mediated Induction of CCL2 in Hyperosmotic Conditions by Cyclosporine and Dexamethasone on Human HeLa-Modified Conjunctiva-Derived Cells
por: Warcoin, Elise, et al.
Publicado: (2016)

Conjunctiva-Associated Lymphoid Tissue (CALT) Reactions to Antiglaucoma Prostaglandins with or without BAK-Preservative in Rabbit Acute Toxicity Study
por: Liang, Hong, et al.
Publicado: (2012)

Toxicological evaluation of preservative-containing and preservative-free topical prostaglandin analogues on a three-dimensional-reconstituted corneal epithelium system
por: Liang, Hong, et al.
Publicado: (2011)

The Eye Drop Preservative Benzalkonium Chloride Potently Induces Mitochondrial Dysfunction and Preferentially Affects LHON Mutant Cells
por: Datta, Sandipan, et al.
Publicado: (2017)

Impact of Dry Eye Disease on Vision Quality: An Optical Quality Analysis System Study
por: Herbaut, Antoine, et al.
Publicado: (2018)

Hyperosmolarity potentiates toxic effects of benzalkonium chloride on conjunctival epithelial cells in vitro
por: Clouzeau, Chloé, et al.
Publicado: (2012)

Effects of Benzalkonium Chloride on THP-1 Differentiated Macrophages In Vitro
por: Michée, Sylvain, et al.
Publicado: (2013)

CXCR3 Antagonism of SDF-1(5-67) Restores Trabecular Function and Prevents Retinal Neurodegeneration in a Rat Model of Ocular Hypertension
por: Denoyer, Alexandre, et al.
Publicado: (2012)

The corneal endothelium in an endotoxin-induced uveitis model: correlation between in vivo confocal microscopy and immunohistochemistry
por: Trinh, Liem, et al.
Publicado: (2008)

Identification of Plasmodium falciparum nuclear proteins by mass spectrometry and proposed protein annotation
por: Briquet, Sylvie, et al.
Publicado: (2018)

Effects of toxic cellular stresses and divalent cations on the human P2X7 cell death receptor
por: Dutot, Mélody, et al.
Publicado: (2008)

Reduction of quaternary ammonium-induced ocular surface toxicity by emulsions: an in vivo study in rabbits
por: Liang, H., et al.
Publicado: (2008)

Protein profile of mouse ovarian follicles grown in vitro
por: Anastácio, Amandine, et al.
Publicado: (2017)

Sublethal Exposure Effects of the Neonicotinoid Clothianidin Strongly Modify the Brain Transcriptome and Proteome in the Male Moth Agrotis ipsilon
por: Meslin, Camille, et al.
Publicado: (2021)

Conjunctival and corneal reactions in rabbits following short- and repeated exposure to preservative-free tafluprost, commercially available latanoprost and 0.02% benzalkonium chloride
por: Liang, H, et al.
Publicado: (2008)

Challenges in the clinical measurement of ocular surface disease in glaucoma patients
por: Pflugfelder, Stephen C, et al.
Publicado: (2011)

A Review of Periocular Botulinum Neurotoxin on the Tear Film Homeostasis and the Ocular Surface Change
por: Ho, Ren-Wen, et al.
Publicado: (2019)

Differential proteomics argues against a general role for CD9, CD81 or CD63 in the sorting of proteins into extracellular vesicles
por: Fan, Yé, et al.
Publicado: (2023)

Multiple endpoint analysis of BAC-preserved and unpreserved antiallergic eye drops on a 3D-reconstituted corneal epithelial model
por: Pauly, A., et al.
Publicado: (2011)

Evaluation of neuroprotective and immunomodulatory properties of mesenchymal stem cells in an ex vivo retinal explant model
por: Reboussin, Élodie, et al.
Publicado: (2022)

Comparative study on the cytotoxic effects of benzalkonium chloride on the Wong-Kilbourne derivative of Chang conjunctival and IOBA-NHC cell lines
por: Brasnu, E., et al.
Publicado: (2008)

Proinflammatory Markers, Chemokines, and Enkephalin in Patients Suffering from Dry Eye Disease
por: Nicolle, Pierre, et al.
Publicado: (2018)

Signs and Symptoms of Ocular Surface Disease: The Reasons for Patient Dissatisfaction with Glaucoma Treatments
por: Stalmans, Ingeborg, et al.
Publicado: (2020)

Effect of artificial tears on dynamic optical quality in patients with dry eye disease
por: Wei, Zhenyu, et al.
Publicado: (2022)

Effect of ocular demodicosis on the stability of the tear film and the tear break up time
por: Sędzikowska, Aleksandra, et al.
Publicado: (2021)

An assessment of the ocular tear film in patients with thyroid disorders
por: Alanazi, Saud A, et al.
Publicado: (2019)

An In Vitro Model for the Ocular Surface and Tear Film System
por: Lu, Qiaozhi, et al.
Publicado: (2017)

Alterations in the ocular surface and tear film following keratoplasty
por: Meyer, Jay J., et al.
Publicado: (2022)

Use of a Cationic Emulsion of Latanoprost to Treat Glaucoma Patients with Ocular Surface Disease: A Preclinical Review
por: Daull, Philippe, et al.
Publicado: (2023)

Reverse Immunology Approach to Define a New HIV-gp41-Neutralizing Epitope
por: Dorgham, Karim, et al.
Publicado: (2019)

Multimodal imaging of Hurler syndrome-related keratopathy treated with deep anterior lamellar keratoplasty
por: Da Cunha, Elodie, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_7r94hc171gre180fjs90fft5hm