Monolayer platform to generate and purify primordial germ-like cells in vitro provides insights into human germline specification

Generating primordial germ cell-like cells (PGCLCs) from human pluripotent stem cells (hPSCs) advances studies of human reproduction and development of infertility treatments, but often entails complex 3D aggregates. Here we develop a simplified, monolayer method to differentiate hPSCs into PGCs wit...

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Detalles Bibliográficos
Autores principales: Vijayakumar, Sivakamasundari, Sala, Roberta, Kang, Gugene, Chen, Angela, Pablo, Michelle Ann, Adebayo, Abidemi Ismail, Cipriano, Andrea, Fowler, Jonas L., Gomes, Danielle L., Ang, Lay Teng, Loh, Kyle M., Sebastiano, Vittorio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502105/
https://www.ncbi.nlm.nih.gov/pubmed/37709760
http://dx.doi.org/10.1038/s41467-023-41302-w

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