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KMT2A associates with PHF5A-PHF14-HMG20A-RAI1 subcomplex in pancreatic cancer stem cells and epigenetically regulates their characteristics

Pancreatic cancer (PC), one of the most aggressive and life-threatening human malignancies, is known for its resistance to cytotoxic therapies. This is increasingly ascribed to the subpopulation of undifferentiated cells, known as pancreatic cancer stem cells (PCSCs), which display greater evolution...

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Detalles Bibliográficos
Autores principales: Mouti, Mai Abdel, Deng, Siwei, Pook, Martin, Malzahn, Jessica, Rendek, Aniko, Militi, Stefania, Nibhani, Reshma, Soonawalla, Zahir, Oppermann, Udo, Hwang, Chang-il, Pauklin, Siim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502114/
https://www.ncbi.nlm.nih.gov/pubmed/37709746
http://dx.doi.org/10.1038/s41467-023-41297-4

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