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KMT2A associates with PHF5A-PHF14-HMG20A-RAI1 subcomplex in pancreatic cancer stem cells and epigenetically regulates their characteristics
Pancreatic cancer (PC), one of the most aggressive and life-threatening human malignancies, is known for its resistance to cytotoxic therapies. This is increasingly ascribed to the subpopulation of undifferentiated cells, known as pancreatic cancer stem cells (PCSCs), which display greater evolution...
Autores principales: | Mouti, Mai Abdel, Deng, Siwei, Pook, Martin, Malzahn, Jessica, Rendek, Aniko, Militi, Stefania, Nibhani, Reshma, Soonawalla, Zahir, Oppermann, Udo, Hwang, Chang-il, Pauklin, Siim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502114/ https://www.ncbi.nlm.nih.gov/pubmed/37709746 http://dx.doi.org/10.1038/s41467-023-41297-4 |
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