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Local BMP2 hydrogel therapy for robust bone regeneration in a porcine model of Legg-Calvé-Perthes disease

Legg-Calvé-Perthes disease is juvenile idiopathic osteonecrosis of the femoral head (ONFH) that has no effective clinical treatment. Previously, local injection of bone morphogenetic protein-2 (BMP2) for ONFH treatment showed a heterogeneous bone repair and a high incidence of heterotopic ossificati...

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Detalles Bibliográficos
Autores principales: Ma, Chi, Park, Min Sung, Alves do Monte, Felipe, Gokani, Vishal, Aruwajoye, Olumide O., Ren, Yinshi, Liu, Xiaohua, Kim, Harry K. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502123/
https://www.ncbi.nlm.nih.gov/pubmed/37709818
http://dx.doi.org/10.1038/s41536-023-00322-2