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Anti-methicillin-resistant Staphylococcus aureus activity and safety evaluation of 14-O-[(5-ethoxycarbonyl-4,6-dimethylpyrimidine-2-yl) thioacetyl] mutilin (EDT)

Infections caused by methicillin-resistant Staphylococcus aureus (MRSA) have threated the public health worldwide, which emphasizes the urgent need for new drugs with novel mechanism of actions. 14-O-[(5-ethoxycarbonyl-4,6-dimethylpyrimidine-2-yl) thioacetyl] mutilin (EDT) is a pleuromutilin compoun...

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Detalles Bibliográficos
Autores principales:	Zhou, Yuhang, Yi, Yunpeng, Yang, Jing, Zhang, Hongjuan, Liu, Qinqin, Wang, Shengyi, Pu, Wanxia, Shang, Ruofeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502144/ https://www.ncbi.nlm.nih.gov/pubmed/37709940 http://dx.doi.org/10.1038/s41598-023-42621-0

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