ctDNA as a novel and promising approach for cancer diagnosis: a focus on hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is one of the most prevalent forms of cancer worldwide. Therefore, it is essential to diagnose and treat HCC patients promptly. As a novel discovery, circulating tumor DNA (ctDNA) can be used to analyze the tumor type and the cancer location. Additionally, ctDNA assist...

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Detalles Bibliográficos
Autores principales: Biglari, Negin, Soltani-Zangbar, Mohammad Sadegh, Mohammadian, Jamal, Mehdizadeh, Amir, Abbasi, Khadijeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2023
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502204/
https://www.ncbi.nlm.nih.gov/pubmed/37720239
http://dx.doi.org/10.17179/excli2023-6277
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author Biglari, Negin
Soltani-Zangbar, Mohammad Sadegh
Mohammadian, Jamal
Mehdizadeh, Amir
Abbasi, Khadijeh
author_facet Biglari, Negin
Soltani-Zangbar, Mohammad Sadegh
Mohammadian, Jamal
Mehdizadeh, Amir
Abbasi, Khadijeh
author_sort Biglari, Negin
collection PubMed
description Hepatocellular carcinoma (HCC) is one of the most prevalent forms of cancer worldwide. Therefore, it is essential to diagnose and treat HCC patients promptly. As a novel discovery, circulating tumor DNA (ctDNA) can be used to analyze the tumor type and the cancer location. Additionally, ctDNA assists the cancer stage determination, which enables medical professionals to provide patients with the most appropriate treatment. This review will discuss the HCC-related mutated genes diagnosed by ctDNA. In addition, we will introduce the different and the most appropriate ctDNA diagnosis approaches based on the facilities.
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spelling pubmed-105022042023-09-16 ctDNA as a novel and promising approach for cancer diagnosis: a focus on hepatocellular carcinoma Biglari, Negin Soltani-Zangbar, Mohammad Sadegh Mohammadian, Jamal Mehdizadeh, Amir Abbasi, Khadijeh EXCLI J Review Article Hepatocellular carcinoma (HCC) is one of the most prevalent forms of cancer worldwide. Therefore, it is essential to diagnose and treat HCC patients promptly. As a novel discovery, circulating tumor DNA (ctDNA) can be used to analyze the tumor type and the cancer location. Additionally, ctDNA assists the cancer stage determination, which enables medical professionals to provide patients with the most appropriate treatment. This review will discuss the HCC-related mutated genes diagnosed by ctDNA. In addition, we will introduce the different and the most appropriate ctDNA diagnosis approaches based on the facilities. Leibniz Research Centre for Working Environment and Human Factors 2023-08-03 /pmc/articles/PMC10502204/ /pubmed/37720239 http://dx.doi.org/10.17179/excli2023-6277 Text en Copyright © 2023 Biglari et al. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Licence (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ) You are free to copy, distribute and transmit the work, provided the original author and source are credited.
spellingShingle Review Article
Biglari, Negin
Soltani-Zangbar, Mohammad Sadegh
Mohammadian, Jamal
Mehdizadeh, Amir
Abbasi, Khadijeh
ctDNA as a novel and promising approach for cancer diagnosis: a focus on hepatocellular carcinoma
title ctDNA as a novel and promising approach for cancer diagnosis: a focus on hepatocellular carcinoma
title_full ctDNA as a novel and promising approach for cancer diagnosis: a focus on hepatocellular carcinoma
title_fullStr ctDNA as a novel and promising approach for cancer diagnosis: a focus on hepatocellular carcinoma
title_full_unstemmed ctDNA as a novel and promising approach for cancer diagnosis: a focus on hepatocellular carcinoma
title_short ctDNA as a novel and promising approach for cancer diagnosis: a focus on hepatocellular carcinoma
title_sort ctdna as a novel and promising approach for cancer diagnosis: a focus on hepatocellular carcinoma
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502204/
https://www.ncbi.nlm.nih.gov/pubmed/37720239
http://dx.doi.org/10.17179/excli2023-6277
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