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Edaravone promotes viability of random skin flaps via activating PI3K/Akt/mTOR signalling pathway‐mediated enhancement of autophagy

Random skin flap transplantation is a commonly used technique. However, ischemia and ischemia–reperfusion injury always impair its therapeutic effectiveness through acclerating oxidative stress, apoptosis and suppressing angiogenesis. To survive, cells rely on mediating autophagy, DNA repair, immuno...

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Detalles Bibliográficos
Autores principales: Bi, Minglei, Qin, Yonghong, Zhao, Liangtao, Zhang, Xuanfen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502271/
https://www.ncbi.nlm.nih.gov/pubmed/37042039
http://dx.doi.org/10.1111/iwj.14184

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