Mechanical stimuli such as shear stress and piezo1 stimulation generate red blood cell extracellular vesicles

Introduction: Generating physiologically relevant red blood cell extracellular vesicles (RBC-EVs) for mechanistic studies is challenging. Herein, we investigated how to generate and isolate high concentrations of RBC-EVs in vitro via shear stress and mechanosensitive piezo1 ion channel stimulation....

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Detalles Bibliográficos
Autores principales: Sangha, Gurneet S., Weber, Callie M., Sapp, Ryan M., Setua, Saini, Thangaraju, Kiruphagaran, Pettebone, Morgan, Rogers, Stephen C., Doctor, Allan, Buehler, Paul W., Clyne, Alisa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502313/
https://www.ncbi.nlm.nih.gov/pubmed/37719461
http://dx.doi.org/10.3389/fphys.2023.1246910

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