Caplacizumab use for immune thrombotic thrombocytopenic purpura: the Milan thrombotic thrombocytopenic purpura registry

• Data on caplacizumab use for thrombotic thrombocytopenic purpura (TTP) in Italy are missing. • Twenty-six Italian patients were treated with caplacizumab for an acute immune TTP episode. • Caplacizumab was effective in treating acute TTP in the Italian real-world clinical setting. • Two major blee...

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Autores principales: Agosti, Pasquale, De Leo, Pasqualina, Capecchi, Marco, Ferrari, Barbara, Mancini, Ilaria, Gattillo, Salvatore, Trisolini, Silvia Maria, Rinaldi, Erminia, Podda, Gian Marco, Prezioso, Lucia, Salutari, Prassede, Facchini, Luca, Caramazza, Domenica, Tolomelli, Giulia, Artoni, Andrea, Peyvandi, Flora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502422/
https://www.ncbi.nlm.nih.gov/pubmed/37720483
http://dx.doi.org/10.1016/j.rpth.2023.102185
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author Agosti, Pasquale
De Leo, Pasqualina
Capecchi, Marco
Ferrari, Barbara
Mancini, Ilaria
Gattillo, Salvatore
Trisolini, Silvia Maria
Rinaldi, Erminia
Podda, Gian Marco
Prezioso, Lucia
Salutari, Prassede
Facchini, Luca
Caramazza, Domenica
Tolomelli, Giulia
Artoni, Andrea
Peyvandi, Flora
author_facet Agosti, Pasquale
De Leo, Pasqualina
Capecchi, Marco
Ferrari, Barbara
Mancini, Ilaria
Gattillo, Salvatore
Trisolini, Silvia Maria
Rinaldi, Erminia
Podda, Gian Marco
Prezioso, Lucia
Salutari, Prassede
Facchini, Luca
Caramazza, Domenica
Tolomelli, Giulia
Artoni, Andrea
Peyvandi, Flora
author_sort Agosti, Pasquale
collection PubMed
description • Data on caplacizumab use for thrombotic thrombocytopenic purpura (TTP) in Italy are missing. • Twenty-six Italian patients were treated with caplacizumab for an acute immune TTP episode. • Caplacizumab was effective in treating acute TTP in the Italian real-world clinical setting. • Two major bleeds leading to drug discontinuation were observed.
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spelling pubmed-105024222023-09-16 Caplacizumab use for immune thrombotic thrombocytopenic purpura: the Milan thrombotic thrombocytopenic purpura registry Agosti, Pasquale De Leo, Pasqualina Capecchi, Marco Ferrari, Barbara Mancini, Ilaria Gattillo, Salvatore Trisolini, Silvia Maria Rinaldi, Erminia Podda, Gian Marco Prezioso, Lucia Salutari, Prassede Facchini, Luca Caramazza, Domenica Tolomelli, Giulia Artoni, Andrea Peyvandi, Flora Res Pract Thromb Haemost Research Letter • Data on caplacizumab use for thrombotic thrombocytopenic purpura (TTP) in Italy are missing. • Twenty-six Italian patients were treated with caplacizumab for an acute immune TTP episode. • Caplacizumab was effective in treating acute TTP in the Italian real-world clinical setting. • Two major bleeds leading to drug discontinuation were observed. Elsevier 2023-08-26 /pmc/articles/PMC10502422/ /pubmed/37720483 http://dx.doi.org/10.1016/j.rpth.2023.102185 Text en © 2023 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Research Letter
Agosti, Pasquale
De Leo, Pasqualina
Capecchi, Marco
Ferrari, Barbara
Mancini, Ilaria
Gattillo, Salvatore
Trisolini, Silvia Maria
Rinaldi, Erminia
Podda, Gian Marco
Prezioso, Lucia
Salutari, Prassede
Facchini, Luca
Caramazza, Domenica
Tolomelli, Giulia
Artoni, Andrea
Peyvandi, Flora
Caplacizumab use for immune thrombotic thrombocytopenic purpura: the Milan thrombotic thrombocytopenic purpura registry
title Caplacizumab use for immune thrombotic thrombocytopenic purpura: the Milan thrombotic thrombocytopenic purpura registry
title_full Caplacizumab use for immune thrombotic thrombocytopenic purpura: the Milan thrombotic thrombocytopenic purpura registry
title_fullStr Caplacizumab use for immune thrombotic thrombocytopenic purpura: the Milan thrombotic thrombocytopenic purpura registry
title_full_unstemmed Caplacizumab use for immune thrombotic thrombocytopenic purpura: the Milan thrombotic thrombocytopenic purpura registry
title_short Caplacizumab use for immune thrombotic thrombocytopenic purpura: the Milan thrombotic thrombocytopenic purpura registry
title_sort caplacizumab use for immune thrombotic thrombocytopenic purpura: the milan thrombotic thrombocytopenic purpura registry
topic Research Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502422/
https://www.ncbi.nlm.nih.gov/pubmed/37720483
http://dx.doi.org/10.1016/j.rpth.2023.102185
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