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Single‐cell transcriptomics identify TNFRSF1B as a novel T‐cell exhaustion marker for ovarian cancer

BACKGROUND: Ovarian cancer (OC) patients routinely show poor immunotherapeutic response due to the complex tumour microenvironment (TME). It is urgent to explore new immunotherapeutic markers. METHODS: Through the single‐cell RNA sequencing (scRNA‐seq) analyses on high‐grade serous OC (HGSOC), moder...

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Detalles Bibliográficos
Autores principales: Gao, Yan, Shi, Hui, Zhao, Hongyu, Yao, Mengcheng, He, Yue, Jiang, Mei, Li, Jie, Li, Zhefeng, Su, Shaofei, Liu, Tao, Yin, Chenghong, Liao, Xuebin, Yue, Wentao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502459/
https://www.ncbi.nlm.nih.gov/pubmed/37712139
http://dx.doi.org/10.1002/ctm2.1416