Depressed glutamate transporter 1 expression in a mouse model of Dravet syndrome

Dravet syndrome (DS) is a monogenic, often refractory, epilepsy resultant from SCN1A haploinsufficiency in humans. A novel therapeutic target in DS that can be engaged in isolation or as adjunctive therapy is highly desirable. Here, we demonstrate reduced expression of the rodent glutamate transport...

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Detalles Bibliográficos
Autores principales: Hameed, Mustafa Q., Hui, Benjamin, Lin, Rui, MacMullin, Paul C., Pascual‐Leone, Andres, Vermudez, Sheryl Anne D., Rotenberg, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Brief Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502630/
https://www.ncbi.nlm.nih.gov/pubmed/37452008
http://dx.doi.org/10.1002/acn3.51851

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