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MLF2 Negatively Regulates P53 and Promotes Colorectal Carcinogenesis

Inactivation of the p53 pathway is linked to a variety of human cancers. As a critical component of the p53 pathway, ubiquitin‐specific protease 7 (USP7) acts as a deubiquitinase for both p53 and its ubiquitin E3 ligase mouse double minute 2 homolog. Here, myeloid leukemia factor 2 (MLF2) is reporte...

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Detalles Bibliográficos
Autores principales: Fang, Debao, Hu, Hao, Zhao, Kailiang, Xu, Aman, Yu, Changjun, Zhu, Yong, Yu, Ning, Yao, Bo, Tang, Suyun, Wu, Xianning, Mei, Yide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502657/
https://www.ncbi.nlm.nih.gov/pubmed/37438558
http://dx.doi.org/10.1002/advs.202303336