Targeting Lymph Nodes for Systemic Immunosuppression Using Cell‐Free‐DNA‐Scavenging And cGAS‐Inhibiting Nanomedicine‐In‐Hydrogel for Rheumatoid Arthritis Immunotherapy

Rheumatoid arthritis (RA) is a systemic autoimmune disease with pathogenic inflammation caused partly by excessive cell‐free DNA (cfDNA). Specifically, cfDNA is internalized into immune cells, such as macrophages in lymphoid tissues and joints, and activates pattern recognition receptors, including...

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Detalles Bibliográficos
Autores principales: Cheng, Furong, Su, Ting, Liu, Yangtengyu, Zhou, Shurong, Qi, Jialong, Guo, Weisheng, Zhu, Guizhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502670/
https://www.ncbi.nlm.nih.gov/pubmed/37435620
http://dx.doi.org/10.1002/advs.202302575

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