In Situ Neutralization and Detoxification of LPS to Attenuate Hyperinflammation (Adv. Sci. 26/2023)

Lipopolysaccharide Hyperinflammation elicited by lipopolysaccharide (LPS) that derives from Gram‐negative pathogens, leads to a sharp increase in mortality globally. In article number 2302950, Xiaoyu Li, Jianzhong Shen, Kui Zhu, and co‐workers have designed an all‐in‐one drug delivery system equippe...

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Detalles Bibliográficos
Autores principales: Li, Xiaoyu, Qu, Shaoqi, Song, Xiangbin, Wu, Congming, Shen, Jianzhong, Zhu, Kui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502678/
http://dx.doi.org/10.1002/advs.202370177
Descripción
Sumario:Lipopolysaccharide Hyperinflammation elicited by lipopolysaccharide (LPS) that derives from Gram‐negative pathogens, leads to a sharp increase in mortality globally. In article number 2302950, Xiaoyu Li, Jianzhong Shen, Kui Zhu, and co‐workers have designed an all‐in‐one drug delivery system equipped with bactericidal activity, LPS neutralization and detoxification to recognize, kill pathogens, and attenuate hyperinflammation through abolishing the activation of LPS triggered acute inflammatory responses. [Image: see text]

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