Cargando…

Beyond Pharmaceuticals: Fit-for-Purpose New Approach Methodologies for Environmental Cardiotoxicity Testing

Environmental factors play a substantial role in determining cardiovascular health, but data informing the risks presented by environmental toxicants is insufficient. In vitro new approach methodologies (NAMs) offer a promising approach with which to address the limitations of traditional in vivo an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Daley, Mark C., Mende, Ulrike, Choi, Bum-Rak, McMullen, Patrick D., Coulombe, Kareen L. K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502740/ https://www.ncbi.nlm.nih.gov/pubmed/35648122 http://dx.doi.org/10.14573/altex.2109131

Ejemplares similares

Action potential metrics and automated data analysis pipeline for cardiotoxicity testing using optically mapped hiPSC-derived 3D cardiac microtissues
por: Soepriatna, Arvin H., et al.
Publicado: (2023)

A predictive in vitro risk assessment platform for pro-arrhythmic toxicity using human 3D cardiac microtissues
por: Kofron, Celinda M., et al.
Publicado: (2021)

Human Cardiac Fibroblast Number and Activation State Modulate Electromechanical Function of hiPSC-Cardiomyocytes in Engineered Myocardium
por: Rupert, Cassady E., et al.
Publicado: (2020)

Pharmaceutical Prevention and Management of Cardiotoxicity in Hematological Malignancies
por: Perpinia, Anastasia Stella, et al.
Publicado: (2022)

Ibrutinib-Associated Cardiotoxicity: From the Pharmaceutical to the Clinical
por: Dong, Rong, et al.
Publicado: (2022)

Poison With a Purpose: A Case Report on Arsenic Cardiotoxicity and Obesity
por: Nachtigal, Emily A, et al.
Publicado: (2022)

One Billion hiPSC-Cardiomyocytes: Upscaling Engineered Cardiac Tissues to Create High Cell Density Therapies for Clinical Translation in Heart Regeneration
por: Dwyer, Kiera D., et al.
Publicado: (2023)

Purpose by design or disaster: Preserving a sense of purpose amid environmental uncertainty
por: Burrow, Anthony L., et al.
Publicado: (2020)

Section 12 approval: fit for purpose?
por: Rigby, David, et al.
Publicado: (2019)

Section 12 approval: fit for purpose?
por: Gupta, Nidhi, et al.
Publicado: (2020)

Section 12 approval: fit for purpose?
por: Ballantyne-Watts, Darryl
Publicado: (2020)

Telemedicine: is the new normal fit for purpose?
por: The Lancet Rheumatology
Publicado: (2022)

Beyond Finding Purpose: Motivating a Translational Science of Purpose Acquisition
por: Burrow, Anthony L.
Publicado: (2023)

Integration of microbubbles with biomaterials in tissue engineering for pharmaceutical purposes
por: Esmaeili, Javad, et al.
Publicado: (2020)

IGF1–PI3K-induced physiological cardiac hypertrophy: Implications for new heart failure therapies, biomarkers, and predicting cardiotoxicity
por: Bass-Stringer, Sebastian, et al.
Publicado: (2021)

Using problem formulation for fit‐for‐purpose pre‐market environmental risk assessments of regulated stressors
por: Devos, Yann, et al.
Publicado: (2019)

Analytical methodologies for determination of methotrexate and its metabolites in pharmaceutical, biological and environmental samples
por: Karami, Forough, et al.
Publicado: (2019)

Leadership of education psychological services: fit for purpose?
por: Booker, Roger
Publicado: (2013)

Review of Applications of Cyclodextrins as Taste-Masking Excipients for Pharmaceutical Purposes
por: Adamkiewicz, Lena, et al.
Publicado: (2023)

Sunitinib and Imatinib Display Differential Cardiotoxicity in Adult Rat Cardiac Fibroblasts That Involves a Role for Calcium/Calmodulin Dependent Protein Kinase II
por: McMullen, Calum J., et al.
Publicado: (2021)

The Roles of Neuregulin-1 in Cardiac Development, Homeostasis, and Disease
por: Rupert, Cassady E, et al.
Publicado: (2015)

Ten principles for generating accessible and useable COVID‐19 environmental science and a fit‐for‐purpose evidence base
por: Kadykalo, Andrew N., et al.
Publicado: (2021)

Readers of poly(ADP-ribose): designed to be fit for purpose
por: Teloni, Federico, et al.
Publicado: (2016)

Clinical trials in the pandemic age: What is fit for purpose?
por: Hartman, Dan, et al.
Publicado: (2020)

Conducting fit‐for‐purpose food safety risk assessments
por: Devos, Yann, et al.
Publicado: (2019)

Is the 10 g monofilament fit for purpose for diagnosing DPN?
por: Malik, Rayaz A
Publicado: (2023)

Model-Based Scale-up Methodologies for Pharmaceutical Granulation
por: Jang, Eun Ha, et al.
Publicado: (2020)

IGF1 and NRG1 Enhance Proliferation, Metabolic Maturity, and the Force-Frequency Response in hESC-Derived Engineered Cardiac Tissues
por: Rupert, Cassady E., et al.
Publicado: (2017)

Cardiac mechanostructure: Using mechanics and anisotropy as inspiration for developing epicardial therapies in treating myocardial infarction
por: Dwyer, Kiera D., et al.
Publicado: (2021)

Stimulating Calcium Handling in hiPSC-Derived Engineered Cardiac Tissues Enhances Force Production
por: Minor, Alicia J, et al.
Publicado: (2022)

Novel methodology for pharmaceutical expenditure forecast
por: Vataire, Anne-Lise, et al.
Publicado: (2014)

Multisource Assessment for Development Purposes: Revisiting the Methodology of Data Analysis
por: Batista-Foguet, Joan Manuel, et al.
Publicado: (2019)

Measuring treatment satisfaction in MS: Is the Treatment Satisfaction Questionnaire for Medication fit for purpose?
por: Vermersch, Patrick, et al.
Publicado: (2016)

Scale-up of Electrospinning: Market Overview of Products and Devices for Pharmaceutical and Biomedical Purposes
por: Omer, Safaa, et al.
Publicado: (2021)

Expert validation of fit-for-purpose guidelines for designing programmes of assessment
por: Dijkstra, Joost, et al.
Publicado: (2012)

Margaret McCartney: The Care Quality Commission is not fit for purpose
por: McCartney, Margaret
Publicado: (2014)

Evaluating New Chemistry to Drive Molecular Discovery: Fit for Purpose?
por: Foley, Daniel J., et al.
Publicado: (2016)

A review of guidance on fish consumption in pregnancy: is it fit for purpose?
por: Taylor, Caroline M, et al.
Publicado: (2018)

Designing Fit for Purpose Health and Social Services for Ageing Populations
por: Woo, Jean
Publicado: (2017)

Section 12(2) MHA approval process is fit for purpose
por: Khwaja, Masum
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_075gt8sginjspuksc852v8subr