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Resistance that stacks up: engineering rust and mildew disease control in the cereal crops wheat and barley
Staying ahead of the arms race against rust and mildew diseases in cereal crops is essential to maintain and preserve food security. The methodological challenges associated with conventional resistance breeding are major bottlenecks for deploying resistance (R) genes in high‐yielding crop varieties...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502761/ https://www.ncbi.nlm.nih.gov/pubmed/37494504 http://dx.doi.org/10.1111/pbi.14106 |
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author | Dracatos, Peter M. Lu, Jing Sánchez‐Martín, Javier Wulff, Brande B.H. |
author_facet | Dracatos, Peter M. Lu, Jing Sánchez‐Martín, Javier Wulff, Brande B.H. |
author_sort | Dracatos, Peter M. |
collection | PubMed |
description | Staying ahead of the arms race against rust and mildew diseases in cereal crops is essential to maintain and preserve food security. The methodological challenges associated with conventional resistance breeding are major bottlenecks for deploying resistance (R) genes in high‐yielding crop varieties. Advancements in our knowledge of plant genomes, structural mechanisms, innovations in bioinformatics, and improved plant transformation techniques have alleviated this bottleneck by permitting rapid gene isolation, functional studies, directed engineering of synthetic resistance and precise genome manipulation in elite crop cultivars. Most cloned cereal R genes encode canonical immune receptors which, on their own, are prone to being overcome through selection for resistance‐evading pathogenic strains. However, the increasingly large repertoire of cloned R genes permits multi‐gene stacking that, in principle, should provide longer‐lasting resistance. This review discusses how these genomics‐enabled developments are leading to new breeding and biotechnological opportunities to achieve durable rust and powdery mildew control in cereals. |
format | Online Article Text |
id | pubmed-10502761 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-105027612023-09-16 Resistance that stacks up: engineering rust and mildew disease control in the cereal crops wheat and barley Dracatos, Peter M. Lu, Jing Sánchez‐Martín, Javier Wulff, Brande B.H. Plant Biotechnol J Review Article Staying ahead of the arms race against rust and mildew diseases in cereal crops is essential to maintain and preserve food security. The methodological challenges associated with conventional resistance breeding are major bottlenecks for deploying resistance (R) genes in high‐yielding crop varieties. Advancements in our knowledge of plant genomes, structural mechanisms, innovations in bioinformatics, and improved plant transformation techniques have alleviated this bottleneck by permitting rapid gene isolation, functional studies, directed engineering of synthetic resistance and precise genome manipulation in elite crop cultivars. Most cloned cereal R genes encode canonical immune receptors which, on their own, are prone to being overcome through selection for resistance‐evading pathogenic strains. However, the increasingly large repertoire of cloned R genes permits multi‐gene stacking that, in principle, should provide longer‐lasting resistance. This review discusses how these genomics‐enabled developments are leading to new breeding and biotechnological opportunities to achieve durable rust and powdery mildew control in cereals. John Wiley and Sons Inc. 2023-07-26 2023-10 /pmc/articles/PMC10502761/ /pubmed/37494504 http://dx.doi.org/10.1111/pbi.14106 Text en © 2023 The Authors. Plant Biotechnology Journal published by Society for Experimental Biology and The Association of Applied Biologists and John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
spellingShingle | Review Article Dracatos, Peter M. Lu, Jing Sánchez‐Martín, Javier Wulff, Brande B.H. Resistance that stacks up: engineering rust and mildew disease control in the cereal crops wheat and barley |
title | Resistance that stacks up: engineering rust and mildew disease control in the cereal crops wheat and barley |
title_full | Resistance that stacks up: engineering rust and mildew disease control in the cereal crops wheat and barley |
title_fullStr | Resistance that stacks up: engineering rust and mildew disease control in the cereal crops wheat and barley |
title_full_unstemmed | Resistance that stacks up: engineering rust and mildew disease control in the cereal crops wheat and barley |
title_short | Resistance that stacks up: engineering rust and mildew disease control in the cereal crops wheat and barley |
title_sort | resistance that stacks up: engineering rust and mildew disease control in the cereal crops wheat and barley |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502761/ https://www.ncbi.nlm.nih.gov/pubmed/37494504 http://dx.doi.org/10.1111/pbi.14106 |
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