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COVID-19-Associated Nephropathy: A Devastating Complication

With the rapid emergence and prevalence of SARS-CoV-2 worldwide, cases of COVID-19-associated nephropathy (COVAN) from collapsing focal segmental glomerulosclerosis (cFSGS) have been reported, and the associations between the two are actively being studied. Creating appropriate treatment guidelines...

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Detalles Bibliográficos
Autores principales: Kim, Andrew, Mahgoub, Abdullahi, Parajuli, Abinash, Towfiq, Basim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502762/
https://www.ncbi.nlm.nih.gov/pubmed/37719542
http://dx.doi.org/10.7759/cureus.43558
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author Kim, Andrew
Mahgoub, Abdullahi
Parajuli, Abinash
Towfiq, Basim
author_facet Kim, Andrew
Mahgoub, Abdullahi
Parajuli, Abinash
Towfiq, Basim
author_sort Kim, Andrew
collection PubMed
description With the rapid emergence and prevalence of SARS-CoV-2 worldwide, cases of COVID-19-associated nephropathy (COVAN) from collapsing focal segmental glomerulosclerosis (cFSGS) have been reported, and the associations between the two are actively being studied. Creating appropriate treatment guidelines for COVAN requires further understanding of the pathophysiology of this type of kidney injury. This case report outlines the case of a 77-year-old patient admitted to the hospital for COVID-19 infection with a subsequent renal biopsy indicating cFSGS, adding to the data exploring the relationship between COVID-19 infections, cFSGS and the associated risk factors. Current guidelines on the treatment of COVAN are similar to those of other causes of cFSGS but continue to have poor outcomes and resistance to treatments. Further research needs to be done on both the clinical assessment and pathophysiology of COVAN to provide timely and life-saving interventions.
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spelling pubmed-105027622023-09-16 COVID-19-Associated Nephropathy: A Devastating Complication Kim, Andrew Mahgoub, Abdullahi Parajuli, Abinash Towfiq, Basim Cureus Internal Medicine With the rapid emergence and prevalence of SARS-CoV-2 worldwide, cases of COVID-19-associated nephropathy (COVAN) from collapsing focal segmental glomerulosclerosis (cFSGS) have been reported, and the associations between the two are actively being studied. Creating appropriate treatment guidelines for COVAN requires further understanding of the pathophysiology of this type of kidney injury. This case report outlines the case of a 77-year-old patient admitted to the hospital for COVID-19 infection with a subsequent renal biopsy indicating cFSGS, adding to the data exploring the relationship between COVID-19 infections, cFSGS and the associated risk factors. Current guidelines on the treatment of COVAN are similar to those of other causes of cFSGS but continue to have poor outcomes and resistance to treatments. Further research needs to be done on both the clinical assessment and pathophysiology of COVAN to provide timely and life-saving interventions. Cureus 2023-08-16 /pmc/articles/PMC10502762/ /pubmed/37719542 http://dx.doi.org/10.7759/cureus.43558 Text en Copyright © 2023, Kim et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Kim, Andrew
Mahgoub, Abdullahi
Parajuli, Abinash
Towfiq, Basim
COVID-19-Associated Nephropathy: A Devastating Complication
title COVID-19-Associated Nephropathy: A Devastating Complication
title_full COVID-19-Associated Nephropathy: A Devastating Complication
title_fullStr COVID-19-Associated Nephropathy: A Devastating Complication
title_full_unstemmed COVID-19-Associated Nephropathy: A Devastating Complication
title_short COVID-19-Associated Nephropathy: A Devastating Complication
title_sort covid-19-associated nephropathy: a devastating complication
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502762/
https://www.ncbi.nlm.nih.gov/pubmed/37719542
http://dx.doi.org/10.7759/cureus.43558
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