Chloroquine Intervenes Nephrotoxicity of Nilotinib through Deubiquitinase USP13‐Mediated Stabilization of Bcl‐XL

Nephrotoxicity has become prominent due to the increase in the clinical use of nilotinib, a second‐generation BCR‐ABL1 inhibitor in the first‐line treatment of Philadelphia chromosome‐positive chronic myeloid leukemia. To date, the mechanism of nilotinib nephrotoxicity is still unknown, leading to a...

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Detalles Bibliográficos
Autores principales: Yan, Hao, Huang, Xiangliang, Xu, Jiangxin, Zhang, Ying, Chen, Jiajia, Xu, Zhifei, Li, Hui, Wang, Zeng, Yang, Xiaochun, Yang, Bo, He, Qiaojun, Luo, Peihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502815/
https://www.ncbi.nlm.nih.gov/pubmed/37452432
http://dx.doi.org/10.1002/advs.202302002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502815/
https://www.ncbi.nlm.nih.gov/pubmed/37452432
http://dx.doi.org/10.1002/advs.202302002

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