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A nomogram model for predicting malnutrition among older hospitalized patients with type 2 diabetes: a cross—sectional study in China
BACKGROUND: Malnutrition remains a pervasive issue among older adults, a prevalence that is markedly higher among those diagnosed with diabetes. The primary objective of this study was to develop and validate a risk prediction model that can accurately identify instances of malnutrition among elderl...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503093/ https://www.ncbi.nlm.nih.gov/pubmed/37715131 http://dx.doi.org/10.1186/s12877-023-04284-4 |
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author | Ran, Qian Zhao, Xili Tian, Jiao Gong, Siyuan Zhang, Xia |
author_facet | Ran, Qian Zhao, Xili Tian, Jiao Gong, Siyuan Zhang, Xia |
author_sort | Ran, Qian |
collection | PubMed |
description | BACKGROUND: Malnutrition remains a pervasive issue among older adults, a prevalence that is markedly higher among those diagnosed with diabetes. The primary objective of this study was to develop and validate a risk prediction model that can accurately identify instances of malnutrition among elderly hospitalized patients with type 2 diabetes mellitus (T2DM) within a Chinese demographic. METHODS: This cross-sectional study was conducted between August 2021 and August 2022, we enrolled T2DM patients aged 65 years and above from endocrinology wards. The creation of a nomogram for predicting malnutrition was based on risk factors identified through univariate and multivariate logistic regression analyses. The predictive accuracy of the model was evaluated by the receiver operating characteristic curve (ROC),the area under the ROC (AUC), the concordance index (C-index), and calibration curves. RESULTS: The study included a total of 248 older T2DM patients, with a recorded malnutrition prevalence of 26.21%. The identified critical risk factors for malnutrition in this cohort were body mass index, albumin, impairment in activities of daily living, dietary habits, and glycosylated hemoglobin. The AUC of the nomogram model reached 0.914 (95% CI: 0.877—0.951), with an optimal cutoff value of 0.392. The model demonstrated a sensitivity of 80.0% and a specificity of 88.5%. Bootstrap-based internal verification results revealed a C-index of 0.891, while the calibration curves indicated a strong correlation between the actual and predicted malnutrition risks. CONCLUSIONS: This study underscores the critical need for early detection of malnutrition in older T2DM patients. The constructed nomogram represents a practical and reliable tool for the rapid identification of malnutrition among this vulnerable population. |
format | Online Article Text |
id | pubmed-10503093 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-105030932023-09-16 A nomogram model for predicting malnutrition among older hospitalized patients with type 2 diabetes: a cross—sectional study in China Ran, Qian Zhao, Xili Tian, Jiao Gong, Siyuan Zhang, Xia BMC Geriatr Research BACKGROUND: Malnutrition remains a pervasive issue among older adults, a prevalence that is markedly higher among those diagnosed with diabetes. The primary objective of this study was to develop and validate a risk prediction model that can accurately identify instances of malnutrition among elderly hospitalized patients with type 2 diabetes mellitus (T2DM) within a Chinese demographic. METHODS: This cross-sectional study was conducted between August 2021 and August 2022, we enrolled T2DM patients aged 65 years and above from endocrinology wards. The creation of a nomogram for predicting malnutrition was based on risk factors identified through univariate and multivariate logistic regression analyses. The predictive accuracy of the model was evaluated by the receiver operating characteristic curve (ROC),the area under the ROC (AUC), the concordance index (C-index), and calibration curves. RESULTS: The study included a total of 248 older T2DM patients, with a recorded malnutrition prevalence of 26.21%. The identified critical risk factors for malnutrition in this cohort were body mass index, albumin, impairment in activities of daily living, dietary habits, and glycosylated hemoglobin. The AUC of the nomogram model reached 0.914 (95% CI: 0.877—0.951), with an optimal cutoff value of 0.392. The model demonstrated a sensitivity of 80.0% and a specificity of 88.5%. Bootstrap-based internal verification results revealed a C-index of 0.891, while the calibration curves indicated a strong correlation between the actual and predicted malnutrition risks. CONCLUSIONS: This study underscores the critical need for early detection of malnutrition in older T2DM patients. The constructed nomogram represents a practical and reliable tool for the rapid identification of malnutrition among this vulnerable population. BioMed Central 2023-09-15 /pmc/articles/PMC10503093/ /pubmed/37715131 http://dx.doi.org/10.1186/s12877-023-04284-4 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Ran, Qian Zhao, Xili Tian, Jiao Gong, Siyuan Zhang, Xia A nomogram model for predicting malnutrition among older hospitalized patients with type 2 diabetes: a cross—sectional study in China |
title | A nomogram model for predicting malnutrition among older hospitalized patients with type 2 diabetes: a cross—sectional study in China |
title_full | A nomogram model for predicting malnutrition among older hospitalized patients with type 2 diabetes: a cross—sectional study in China |
title_fullStr | A nomogram model for predicting malnutrition among older hospitalized patients with type 2 diabetes: a cross—sectional study in China |
title_full_unstemmed | A nomogram model for predicting malnutrition among older hospitalized patients with type 2 diabetes: a cross—sectional study in China |
title_short | A nomogram model for predicting malnutrition among older hospitalized patients with type 2 diabetes: a cross—sectional study in China |
title_sort | nomogram model for predicting malnutrition among older hospitalized patients with type 2 diabetes: a cross—sectional study in china |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503093/ https://www.ncbi.nlm.nih.gov/pubmed/37715131 http://dx.doi.org/10.1186/s12877-023-04284-4 |
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