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Astaxanthin attenuates cognitive deficits in Alzheimer’s disease models by reducing oxidative stress via the SIRT1/PGC-1α signaling pathway

OBJECTIVE: Oxidative stress plays a pivotal role in neurodegenerative diseases. Astaxanthin (AST) can play a neuroprotective role owing to its long-chain conjugated unsaturated double bond, which imparts potent antioxidant, anti-neuroinflammatory, and anti-apoptotic properties. However, the biologic...

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Detalles Bibliográficos
Autores principales: Liu, Ning, Lyu, Xiaohong, Zhang, Xianglin, Zhang, Fan, Chen, Yiming, Li, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503143/
https://www.ncbi.nlm.nih.gov/pubmed/37710272
http://dx.doi.org/10.1186/s13578-023-01129-w