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Astaxanthin attenuates cognitive deficits in Alzheimer’s disease models by reducing oxidative stress via the SIRT1/PGC-1α signaling pathway
OBJECTIVE: Oxidative stress plays a pivotal role in neurodegenerative diseases. Astaxanthin (AST) can play a neuroprotective role owing to its long-chain conjugated unsaturated double bond, which imparts potent antioxidant, anti-neuroinflammatory, and anti-apoptotic properties. However, the biologic...
Autores principales: | Liu, Ning, Lyu, Xiaohong, Zhang, Xianglin, Zhang, Fan, Chen, Yiming, Li, Gang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503143/ https://www.ncbi.nlm.nih.gov/pubmed/37710272 http://dx.doi.org/10.1186/s13578-023-01129-w |
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