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Evaluation of commercial kits for isolation and bisulfite conversion of circulating cell-free tumor DNA from blood

BACKGROUND: DNA methylation biomarkers in circulating cell-free DNA (cfDNA) have great clinical potential for cancer management. Most methods for DNA methylation analysis require bisulfite conversion, causing DNA degradation and loss. This is particularly challenging for cfDNA, which is naturally fr...

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Detalles Bibliográficos
Autores principales:	Kresse, Stine H., Brandt-Winge, Sara, Pharo, Heidi, Flatin, Bjørnar T. B., Jeanmougin, Marine, Vedeld, Hege Marie, Lind, Guro E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503171/ https://www.ncbi.nlm.nih.gov/pubmed/37710283 http://dx.doi.org/10.1186/s13148-023-01563-0

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