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Foot drop in children with newly diagnosed type 1 diabetes: three case reports

SUMMARY: The etiology of foot drop is diverse from various diseases to mechanic injuries and includes neuropathy of the peroneal nerve. Peroneal neuropathy might also be one of the forms of diabetic neuropathy, very rarely reported as the first sign of diabetes. We describe three cases of children w...

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Autores principales: Chrzanowska, Joanna, Seifert, Monika, Salmonowicz, Barbara, Zubkiewicz-Kucharska, Agnieszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503214/
https://www.ncbi.nlm.nih.gov/pubmed/37650300
http://dx.doi.org/10.1530/EDM-22-0417
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author Chrzanowska, Joanna
Seifert, Monika
Salmonowicz, Barbara
Zubkiewicz-Kucharska, Agnieszka
author_facet Chrzanowska, Joanna
Seifert, Monika
Salmonowicz, Barbara
Zubkiewicz-Kucharska, Agnieszka
author_sort Chrzanowska, Joanna
collection PubMed
description SUMMARY: The etiology of foot drop is diverse from various diseases to mechanic injuries and includes neuropathy of the peroneal nerve. Peroneal neuropathy might also be one of the forms of diabetic neuropathy, very rarely reported as the first sign of diabetes. We describe three cases of children with newly diagnosed type 1 diabetes (TID) who developed unilateral peroneal nerve palsies and tibial nerve palsies, presenting clinically as a foot drop. In two of our cases, the symptoms of foot drop occurred shortly after starting treatment for severe diabetes ketoacidosis. In the third patient, food drop was a reason for the initial medical consultation, but eventually, TID was diagnosed. The presented cases highlight that neuropathy can be observed not only as a chronic complication of T1D, but it can also appear at the time of disease manifestation. The incorrect position of the lower limb during a keto coma may contribute to the development of neuropathy. LEARNING POINTS: Neuropathy can be observed not only as a chronic complication of type 1 diabetes (T1D), but it can also appear at the time of disease manifestation. The incorrect position of the lower limb causing external pressure during a keto coma may contribute to the development of neuropathy. It is important to examine the glycemia in patients with acute peroneal neuropathy, as this kind of peripheral neuropathy can be associated with newly diagnosed T1D. Normalization of glycemia might lead to rapid neuronal recovery.
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spelling pubmed-105032142023-09-16 Foot drop in children with newly diagnosed type 1 diabetes: three case reports Chrzanowska, Joanna Seifert, Monika Salmonowicz, Barbara Zubkiewicz-Kucharska, Agnieszka Endocrinol Diabetes Metab Case Rep Unique/Unexpected Symptoms or Presentations of a Disease SUMMARY: The etiology of foot drop is diverse from various diseases to mechanic injuries and includes neuropathy of the peroneal nerve. Peroneal neuropathy might also be one of the forms of diabetic neuropathy, very rarely reported as the first sign of diabetes. We describe three cases of children with newly diagnosed type 1 diabetes (TID) who developed unilateral peroneal nerve palsies and tibial nerve palsies, presenting clinically as a foot drop. In two of our cases, the symptoms of foot drop occurred shortly after starting treatment for severe diabetes ketoacidosis. In the third patient, food drop was a reason for the initial medical consultation, but eventually, TID was diagnosed. The presented cases highlight that neuropathy can be observed not only as a chronic complication of T1D, but it can also appear at the time of disease manifestation. The incorrect position of the lower limb during a keto coma may contribute to the development of neuropathy. LEARNING POINTS: Neuropathy can be observed not only as a chronic complication of type 1 diabetes (T1D), but it can also appear at the time of disease manifestation. The incorrect position of the lower limb causing external pressure during a keto coma may contribute to the development of neuropathy. It is important to examine the glycemia in patients with acute peroneal neuropathy, as this kind of peripheral neuropathy can be associated with newly diagnosed T1D. Normalization of glycemia might lead to rapid neuronal recovery. Bioscientifica Ltd 2023-08-31 /pmc/articles/PMC10503214/ /pubmed/37650300 http://dx.doi.org/10.1530/EDM-22-0417 Text en © the author(s) https://creativecommons.org/licenses/by-nc/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. (https://creativecommons.org/licenses/by-nc/4.0/)
spellingShingle Unique/Unexpected Symptoms or Presentations of a Disease
Chrzanowska, Joanna
Seifert, Monika
Salmonowicz, Barbara
Zubkiewicz-Kucharska, Agnieszka
Foot drop in children with newly diagnosed type 1 diabetes: three case reports
title Foot drop in children with newly diagnosed type 1 diabetes: three case reports
title_full Foot drop in children with newly diagnosed type 1 diabetes: three case reports
title_fullStr Foot drop in children with newly diagnosed type 1 diabetes: three case reports
title_full_unstemmed Foot drop in children with newly diagnosed type 1 diabetes: three case reports
title_short Foot drop in children with newly diagnosed type 1 diabetes: three case reports
title_sort foot drop in children with newly diagnosed type 1 diabetes: three case reports
topic Unique/Unexpected Symptoms or Presentations of a Disease
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503214/
https://www.ncbi.nlm.nih.gov/pubmed/37650300
http://dx.doi.org/10.1530/EDM-22-0417
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