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Foot drop in children with newly diagnosed type 1 diabetes: three case reports
SUMMARY: The etiology of foot drop is diverse from various diseases to mechanic injuries and includes neuropathy of the peroneal nerve. Peroneal neuropathy might also be one of the forms of diabetic neuropathy, very rarely reported as the first sign of diabetes. We describe three cases of children w...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Bioscientifica Ltd
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503214/ https://www.ncbi.nlm.nih.gov/pubmed/37650300 http://dx.doi.org/10.1530/EDM-22-0417 |
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author | Chrzanowska, Joanna Seifert, Monika Salmonowicz, Barbara Zubkiewicz-Kucharska, Agnieszka |
author_facet | Chrzanowska, Joanna Seifert, Monika Salmonowicz, Barbara Zubkiewicz-Kucharska, Agnieszka |
author_sort | Chrzanowska, Joanna |
collection | PubMed |
description | SUMMARY: The etiology of foot drop is diverse from various diseases to mechanic injuries and includes neuropathy of the peroneal nerve. Peroneal neuropathy might also be one of the forms of diabetic neuropathy, very rarely reported as the first sign of diabetes. We describe three cases of children with newly diagnosed type 1 diabetes (TID) who developed unilateral peroneal nerve palsies and tibial nerve palsies, presenting clinically as a foot drop. In two of our cases, the symptoms of foot drop occurred shortly after starting treatment for severe diabetes ketoacidosis. In the third patient, food drop was a reason for the initial medical consultation, but eventually, TID was diagnosed. The presented cases highlight that neuropathy can be observed not only as a chronic complication of T1D, but it can also appear at the time of disease manifestation. The incorrect position of the lower limb during a keto coma may contribute to the development of neuropathy. LEARNING POINTS: Neuropathy can be observed not only as a chronic complication of type 1 diabetes (T1D), but it can also appear at the time of disease manifestation. The incorrect position of the lower limb causing external pressure during a keto coma may contribute to the development of neuropathy. It is important to examine the glycemia in patients with acute peroneal neuropathy, as this kind of peripheral neuropathy can be associated with newly diagnosed T1D. Normalization of glycemia might lead to rapid neuronal recovery. |
format | Online Article Text |
id | pubmed-10503214 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Bioscientifica Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-105032142023-09-16 Foot drop in children with newly diagnosed type 1 diabetes: three case reports Chrzanowska, Joanna Seifert, Monika Salmonowicz, Barbara Zubkiewicz-Kucharska, Agnieszka Endocrinol Diabetes Metab Case Rep Unique/Unexpected Symptoms or Presentations of a Disease SUMMARY: The etiology of foot drop is diverse from various diseases to mechanic injuries and includes neuropathy of the peroneal nerve. Peroneal neuropathy might also be one of the forms of diabetic neuropathy, very rarely reported as the first sign of diabetes. We describe three cases of children with newly diagnosed type 1 diabetes (TID) who developed unilateral peroneal nerve palsies and tibial nerve palsies, presenting clinically as a foot drop. In two of our cases, the symptoms of foot drop occurred shortly after starting treatment for severe diabetes ketoacidosis. In the third patient, food drop was a reason for the initial medical consultation, but eventually, TID was diagnosed. The presented cases highlight that neuropathy can be observed not only as a chronic complication of T1D, but it can also appear at the time of disease manifestation. The incorrect position of the lower limb during a keto coma may contribute to the development of neuropathy. LEARNING POINTS: Neuropathy can be observed not only as a chronic complication of type 1 diabetes (T1D), but it can also appear at the time of disease manifestation. The incorrect position of the lower limb causing external pressure during a keto coma may contribute to the development of neuropathy. It is important to examine the glycemia in patients with acute peroneal neuropathy, as this kind of peripheral neuropathy can be associated with newly diagnosed T1D. Normalization of glycemia might lead to rapid neuronal recovery. Bioscientifica Ltd 2023-08-31 /pmc/articles/PMC10503214/ /pubmed/37650300 http://dx.doi.org/10.1530/EDM-22-0417 Text en © the author(s) https://creativecommons.org/licenses/by-nc/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. (https://creativecommons.org/licenses/by-nc/4.0/) |
spellingShingle | Unique/Unexpected Symptoms or Presentations of a Disease Chrzanowska, Joanna Seifert, Monika Salmonowicz, Barbara Zubkiewicz-Kucharska, Agnieszka Foot drop in children with newly diagnosed type 1 diabetes: three case reports |
title | Foot drop in children with newly diagnosed type 1 diabetes: three case reports |
title_full | Foot drop in children with newly diagnosed type 1 diabetes: three case reports |
title_fullStr | Foot drop in children with newly diagnosed type 1 diabetes: three case reports |
title_full_unstemmed | Foot drop in children with newly diagnosed type 1 diabetes: three case reports |
title_short | Foot drop in children with newly diagnosed type 1 diabetes: three case reports |
title_sort | foot drop in children with newly diagnosed type 1 diabetes: three case reports |
topic | Unique/Unexpected Symptoms or Presentations of a Disease |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503214/ https://www.ncbi.nlm.nih.gov/pubmed/37650300 http://dx.doi.org/10.1530/EDM-22-0417 |
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