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Efficacy, safety, and biomarker analysis of nivolumab in combination with abemaciclib plus endocrine therapy in patients with HR-positive HER2-negative metastatic breast cancer: a phase II study (WJOG11418B NEWFLAME trial)

BACKGROUND: Hormone receptor (HR)-positive breast cancer is a disease for which no immune checkpoint inhibitors have shown promise as effective therapies. Cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitors synergistically increased the effectiveness of antiprogrammed cell death protein-1 (anti-PD-1...

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Detalles Bibliográficos
Autores principales:	Masuda, Jun, Sakai, Hitomi, Tsurutani, Junji, Tanabe, Yuko, Masuda, Norikazu, Iwasa, Tsutomu, Takahashi, Masato, Futamura, Manabu, Matsumoto, Koji, Aogi, Kenjiro, Iwata, Hiroji, Hosonaga, Mari, Mukohara, Toru, Yoshimura, Kiyoshi, Imamura, Chiyo K, Miura, Sakiko, Yamochi, Toshiko, Kawabata, Hidetaka, Yasojima, Hiroyuki, Tomioka, Nobumoto, Yoshimura, Kenichi, Takano, Toshimi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2023
Materias:	Clinical/Translational Cancer Immunotherapy
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503337/ https://www.ncbi.nlm.nih.gov/pubmed/37709297 http://dx.doi.org/10.1136/jitc-2023-007126

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