Immune checkpoint blockade therapy mitigates systemic inflammation and affects cellular FLIP-expressing monocytic myeloid-derived suppressor cells in non-progressor non-small cell lung cancer patients

Cancer cells favor the generation of myeloid cells with immunosuppressive and inflammatory features, including myeloid-derived suppressor cells (MDSCs), which support tumor progression. The anti-apoptotic molecule, cellular FLICE (FADD-like interleukin-1β-converting enzyme)-inhibitory protein (c-FLI...

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Detalles Bibliográficos
Autores principales: Adamo, Annalisa, Frusteri, Cristina, Pilotto, Sara, Caligola, Simone, Belluomini, Lorenzo, Poffe, Ornella, Giacobazzi, Luca, Dusi, Silvia, Musiu, Chiara, Hu, Yushu, Wang, Tian, Rizzini, Davide, Vella, Antonio, Canè, Stefania, Sartori, Giulia, Insolda, Jessica, Sposito, Marco, Incani, Ursula Cesta, Carbone, Carmine, Piro, Geny, Pettinella, Francesca, Qi, Fang, Wang, Dali, Sartoris, Silvia, De Sanctis, Francesco, Scapini, Patrizia, Dusi, Stefano, Cassatella, Marco Antonio, Bria, Emilio, Milella, Michele, Bronte, Vincenzo, Ugel, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503454/
https://www.ncbi.nlm.nih.gov/pubmed/37720688
http://dx.doi.org/10.1080/2162402X.2023.2253644

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