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Congenital Ichthyosis: A Practical Clinical Guide on Current Treatments and Future Perspectives
Congenital ichthyoses are a group of hereditary disorders of keratinization that are challenging to treat. Affected individuals suffer not only from thickening of the skin but also associated complications such as growth restriction, hearing and eye complications, infections, and thermodysregulation...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503504/ https://www.ncbi.nlm.nih.gov/pubmed/37719935 http://dx.doi.org/10.2147/CCID.S388608 |
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author | Lilly, Evelyn Bunick, Christopher G |
author_facet | Lilly, Evelyn Bunick, Christopher G |
author_sort | Lilly, Evelyn |
collection | PubMed |
description | Congenital ichthyoses are a group of hereditary disorders of keratinization that are challenging to treat. Affected individuals suffer not only from thickening of the skin but also associated complications such as growth restriction, hearing and eye complications, infections, and thermodysregulation. This clinical review provides a practical roadmap to the longitudinal care of patients with ichthyosis with both general and age- and disease-specific recommendations. The allure of pathogenesis-based and targeted treatments for these monogenetic severe but orphan conditions shines bright as dermatological therapies enter a new era. |
format | Online Article Text |
id | pubmed-10503504 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Dove |
record_format | MEDLINE/PubMed |
spelling | pubmed-105035042023-09-16 Congenital Ichthyosis: A Practical Clinical Guide on Current Treatments and Future Perspectives Lilly, Evelyn Bunick, Christopher G Clin Cosmet Investig Dermatol Review Congenital ichthyoses are a group of hereditary disorders of keratinization that are challenging to treat. Affected individuals suffer not only from thickening of the skin but also associated complications such as growth restriction, hearing and eye complications, infections, and thermodysregulation. This clinical review provides a practical roadmap to the longitudinal care of patients with ichthyosis with both general and age- and disease-specific recommendations. The allure of pathogenesis-based and targeted treatments for these monogenetic severe but orphan conditions shines bright as dermatological therapies enter a new era. Dove 2023-09-11 /pmc/articles/PMC10503504/ /pubmed/37719935 http://dx.doi.org/10.2147/CCID.S388608 Text en © 2023 Lilly and Bunick. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). |
spellingShingle | Review Lilly, Evelyn Bunick, Christopher G Congenital Ichthyosis: A Practical Clinical Guide on Current Treatments and Future Perspectives |
title | Congenital Ichthyosis: A Practical Clinical Guide on Current Treatments and Future Perspectives |
title_full | Congenital Ichthyosis: A Practical Clinical Guide on Current Treatments and Future Perspectives |
title_fullStr | Congenital Ichthyosis: A Practical Clinical Guide on Current Treatments and Future Perspectives |
title_full_unstemmed | Congenital Ichthyosis: A Practical Clinical Guide on Current Treatments and Future Perspectives |
title_short | Congenital Ichthyosis: A Practical Clinical Guide on Current Treatments and Future Perspectives |
title_sort | congenital ichthyosis: a practical clinical guide on current treatments and future perspectives |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503504/ https://www.ncbi.nlm.nih.gov/pubmed/37719935 http://dx.doi.org/10.2147/CCID.S388608 |
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