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5-Bromo-2’-deoxyuridine labeling: historical perspectives, factors influencing the detection, toxicity, and its implications in the neurogenesis

The halopyrimidine 5-bromo-2′-deoxyuridine (BrdU) is an exogenous marker of DNA synthesis. Since the introduction of monoclonal antibodies against BrdU, an increasing number of methodologies have been used for the immunodetection of this synthesized bromine-tagged base analogue into replicating DNA....

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Detalles Bibliográficos
Autor principal: Martí-Clúa, Joaquín
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503596/
https://www.ncbi.nlm.nih.gov/pubmed/37488882
http://dx.doi.org/10.4103/1673-5374.379038