Inducible overexpression of a FAM3C/ILEI transgene has pleiotropic effects with shortened life span, liver fibrosis and anemia in mice

FAM3C/ILEI is an important factor in epithelial-to-mesenchymal transition (EMT) induction, tumor progression and metastasis. Overexpressed in many cancers, elevated ILEI levels and secretion correlate with poor patient survival. Although ILEI’s causative role in invasive tumor growth and metastasis...

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Detalles Bibliográficos
Autores principales: Schmidt, Ulrike, Uluca, Betül, Vokic, Iva, Malik, Barizah, Kolbe, Thomas, Lassnig, Caroline, Holcmann, Martin, Moreno-Viedma, Veronica, Robl, Bernhard, Mühlberger, Carina, Gotthardt, Dagmar, Sibilia, Maria, Rülicke, Thomas, Müller, Mathias, Csiszar, Agnes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503705/
https://www.ncbi.nlm.nih.gov/pubmed/37713409
http://dx.doi.org/10.1371/journal.pone.0286256

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