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Evidence for preexisting prion substrain diversity in a biologically cloned prion strain
Prion diseases are a group of inevitably fatal neurodegenerative disorders affecting numerous mammalian species, including Sapiens. Prions are composed of PrP(Sc), the disease specific conformation of the host encoded prion protein. Prion strains are operationally defined as a heritable phenotype of...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503715/ https://www.ncbi.nlm.nih.gov/pubmed/37669293 http://dx.doi.org/10.1371/journal.ppat.1011632 |