Multiplex interrogation of the NK cell signalome reveals global downregulation of CD16 signaling during lentivirus infection through an IL-18/ADAM17-dependent mechanism

Despite their importance, natural killer (NK) cell responses are frequently dysfunctional during human immunodeficiency virus-1 (HIV-1) and simian immunodeficiency virus (SIV) infections, even irrespective of antiretroviral therapies, with poorly understood underlying mechanisms. NK cell surface rec...

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Detalles Bibliográficos
Autores principales: Sugawara, Sho, Hueber, Brady, Woolley, Griffin, Terry, Karen, Kroll, Kyle, Manickam, Cordelia, Ram, Daniel R., Ndhlovu, Lishomwa C., Goepfert, Paul, Jost, Stephanie, Reeves, R. Keith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503717/
https://www.ncbi.nlm.nih.gov/pubmed/37669308
http://dx.doi.org/10.1371/journal.ppat.1011629

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